Caspases
Apoptosis is primarily induced by the activation of caspases. Active caspases recognize a large number of different substrates, leading to the activation of several different apoptotic pathways. The cleavage of several structural proteins by caspases leads to the unique apoptosis cell morphology of chromatin condensation, nuclear fragmentation and cytoplasmic integrity. The most common method to measure caspase activity is via fluorometric or colorimetric detection of the cleavage of caspase-specific substrates.
Cell: Jurkat
Caspase-3 activator: anti-Fas/CD95 (clone CH-11)
Caspase-3 inhibitor: DEVD-FMK
Caspase Assay Products
| Code No. | Name | Size | Notes |
|---|---|---|---|
| 4800 | Caspase-3 Colorometric Assay Kit | 100 assays | Highly Cited |
| 4805 | APOPCYTO Caspase-8 Colorimetric Assay Kit | 100 assays | |
| 4810 | Caspase 9 Colorimetric Assay Kit | 100 assays | |
| 4815 | APOPCYTO Caspase-3 Fluorometric Assay Kit | 100 assays | |
| 4820 | Caspase 8 Fluorometric Assay Kit | 100 assays | |
| 4825 | APOPCYTO Caspase-9 Fluorometric Assay Kit | 100 assays |
