Novel Neoantigen Screening Tool:  QuickSwitch™ Custom Tetramer Kits

A rapid high throughput and user friendly system for creating new tetramer specificities. Tetramers resulting from peptide exchange with selected peptides can be used for immune monitoring.

Useful for research involving cancer neoantigens, infectious agents and many other research areas.

Learn more about our QuickSwitch™ products.

• Claim your free 2 pack TransFix – with the purchase of our ExoCap kit.

• Replace your discontinued antibodies– with discount available for valid replacement.
• Share your review – write about your experience using an MBLI product and receive an award. Terms and Conditions apply.

COLLABORATE WITH MBLI

Partnering with pharmaceutical, biotechnology, and diagnostics companies to out-license our innovative technologies and products supporting life science research, develop companion diagnostics and in-license IVD technologies/products in the areas of cancer, autoimmune diseases, infectious diseases, allergy and cytological/pathological testing.

MBL International will be attending:

• November 7 – 11 SITC 2018 in Washington, DC

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Press Release

JSR’s Life Sciences Division Appoints New CEO for MBL International

Jan. 23, 2018 – Sunnyvale, CA – JSR Life Sciences, the life sciences-focused business unit of JSR Corporation, announced today that it has appointed Dr. Nalini Murdter as the President and Chief Executive Officer of MBL International (MBLI) effective immediately.

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May 22nd, 2017: MEDICAL & BIOLOGICAL LABORATORIES Co., Ltd. (MBL) announced that it has entered into a collaboration agreement with the p53 Laboratory, Agency for Science, Technology and Research (A*STAR) in Singapore to establish the novel screening technology which accelerates the drug discovery targeting Protein-Protein Interactions (PPIs).

February 28th, 2017: MEDICAL & BIOLOGICAL LABORATORIES Co., Ltd. concludes a patent licensing agreement with the University of Toyama concerning a rapid antibody production technique

• ELISA Kits and Antibodies – 2 new ELISA kits and new antibodies
• Fluoppi Protein-Protein Interaction – Visualize and Screen PPI’s with 18 new pre-made vector sets of popular oncology targets
• Next-Generation Nano Culture Plates – 3D Cell Culture plates for tumor modeling and other applications, easy to use with improved imaging
• TransFix® – A patented stabilization solution that is easy to use and preserves cells and cellular antigens for up to 14 days prior to analysis
• Trial Size Antibodies– 134 new trial size antibodies now available

• Gating strategy for tetramer analysis to eliminate non-specific event

  Wed, 14 Nov 2018 18:00:00 GMTBy:

  While MHC tetramer staining of antigen specific T cells for flow cytometry is considered highly specific, it could still be associated with non-specific staining. The gating strategy shown below is an example that investigators have used to reduce non-specific staining events using a dump channel. A dump channel can be planned on a case by case basis, on the experimental design, and consists of a pool of antibodies against cells that do not express our specific targets. For example, CD8+ T cells, anti-CD4/anti-CD14/anti-CD19 may be used to eliminate these immune cells from our targeted gate, and all may be labeled with the same fluorochrome.  Read more

• Shed a little light in your cells using anti-GFP

  Wed, 24 Oct 2018 17:02:00 GMTBy: bindi.doshi@mblintl.com (Bindi M. Doshi, PhD)

  In 2008, the Nobel Prize in Chemistry was awarded to Dr. Roger Y. Tsien, Dr. Osamu Shimomura, and Dr. Martin Chalfie for their discovery and development of the green fluorescent protein (GFP).  Since then, fluorescent protein (FP) technology has made drastic advancements by many researchers.  FP antibodies are used in multiple applications. Read more

• Fc blockers to reduce background in Tetramer staining

  Tue, 25 Sep 2018 17:00:00 GMTBy: nakajo.tomohiro@mbl.co.jp (Tomohiro Nakajo)

  Fc blockers are needed for monocytes, macrophages, B cells and granulocytes. Since T cells normally do not express Fc receptors, some investigators do not use Fc blockers and instead use a dump channel (e.g. CD14/CD19) during flow cytometry analysis to exclude Fc-expressing populations.  Read more

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