Autophagy

Autophagy is a cellular self-digestion process for the purpose of providing nutrients to allow for cell survival during stress conditions. Autophagy can be selective (mitophagy) or non-selective (nutrient poor). Autophagy plays an important role in maintaining the cell homeostasis by removing non-essential cell components. Recent research has also shown an association of mammalian autophagy with pathological conditions including neurodegenerative diseases, infection, cardiac disease, cancer and aging.

  • Hundreds of citations across our autophagy products line
  • Validated in Western Blot, Immunohistochemistry, Flow Cytometry, Immunoprecipitation and other applications
  • LC3, p62, Atg9, Atg12, Atg14 and many other targets   

Autophagy Products Highlights

Antibodies against LC3/ATG8

AutoNew

Detection of LC3 using PM036

Antibodies against p62/SQSTM1

Autophagyp62

Detection of p62-positive inclusion bodies in the human hepatocellular carcinoma using PM045

Related Product Highlight

Keima-Red for mitophagy detection in living cells

Mitophagy4

Mitophagy is the process of selective mitochondrial degradation by autophagy. It has been found to be involved in neurodegenerative and cardiovascular diseases as well as cancer.

Discover more about other Autophagy targets and products