Autophagy is a cellular self-digestion process for the purpose of providing nutrients to allow for cell survival during stress conditions. Autophagy can be selective (mitophagy) or non-selective (nutrient poor). Autophagy plays an important role in maintaining the cell homeostasis by removing non-essential cell components. Recent research has also shown an association of mammalian autophagy with pathological conditions including neurodegenerative diseases, infection, cardiac disease, cancer and aging.
- Hundreds of citations across our autophagy products line
- Validated in Western Blot, Immunohistochemistry, Flow Cytometry, Immunoprecipitation and other applications
- LC3, p62, Atg9, Atg12, Atg14 and many other targets
Autophagy Products Highlights
Antibodies against p62/SQSTM1
Detection of p62-positive inclusion bodies in the human hepatocellular carcinoma using PM045
Related Product Highlight
Keima-Red for mitophagy detection in living cells
Mitophagy is the process of selective mitochondrial degradation by autophagy. It has been found to be involved in neurodegenerative and cardiovascular diseases as well as cancer.