MHC Class I & II Tetramers MHC Monomers CD1d Tetramers
TCRs recognize and bind to complexes composed of MHC molecules and specific peptides expressed on the surface of antigen-presenting cells. We have tetramerized and biotinylated with streptavidin to maintain stable binding to multiple TCR, enabling MHC/peptide tetramers to be used as detection tools. Phycoerythrin (PE), allophycocyanin (APC), or Brilliant Violet™ 421 (BV421) fluorophores are available for detection of antigen-specific T cells by flow cytometry or fluorescence microscopy using our MHC Multimers.
- MBL tetramers offer Superior Specificity with α3 Mutation*
- Class I and Class II Available
- PE, APC and BV421 Conjugates Available
- Create your own custom tetramers with QuickSwitch™
- Available MHC Alleles
- Custom Services Available
*Only human and macaque HLA Class I Tetramers contain the alpha 3 mutation.
Learn about the types of MHC Molecules
Superior Specificity with Patented α3 Mutation*
*Only human and macaque HLA Class I Tetramers contain the alpha 3 mutation.
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