MHC Class I & II Tetramers MHC Monomers CD1d Tetramers

TCRs recognize and bind to complexes composed of MHC molecules and specific peptides expressed on the surface of antigen-presenting cells. We have tetramerized and biotinylated with streptavidin to maintain stable binding to multiple TCR, enabling MHC/peptide tetramers to be used as detection tools. Phycoerythrin (PE), allophycocyanin (APC), or Brilliant Violet 421 (BV421) fluorophores are available for detection of antigen-specific T cells by flow cytometry or fluorescence microscopy using our MHC Multimers.

*Only Human HLA Class I Tetramers contain the alpha 3 mutation.

Learn about the types of MHC Molecules

Superior Specificity with Patented α3 Mutation*

Impact of α3 Mutation

*Only Human HLA Class I Tetramers contain the alpha 3 mutation.

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