The TdT-mediated dUTP-biotin nick end labeling method (TUNEL method) enables in situ visualization of DNA fragmentation at the single cell level by labeling the terminal ends of nucleic acids. The MEBSTAIN Apoptosis Kit Direct is an apoptosis detection kit based on the TUNEL method. The main advantage of this rapid and simple procedure is the use of fluorescein-dUTP to label DNA strand breaks. This allows the direct detection of DNA fragmentation. It is a more sensitive method than conventional morphological techniques.
MEBSTAIN Apoptosis TUNEL Kit Product
| Code No. | Name | Size | Notes |
|---|---|---|---|
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MEBSTAIN Apoptosis TUNEL Kit Direct
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FCM:66 tests/stain:40 tests
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Highly Cited
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Learn more about other popular Apoptosis targets and products
GENERAL APOPTOTIC PRODUCTS
MBL International offers over 600 products including proteins, antibodies and kits to aid in the study of the apoptotic pathway. These products cover a wide variety of applications.
DNA FRAGMENTATION DETECTION
The TdT-mediated dUTP-biotin nick end labeling method (TUNEL method) enables in situ visualization of DNA fragmentation at the single cell level by labeling the terminal ends of nucleic acids. The MEBSTAIN Apoptosis Kit Direct is an apoptosis detection kit based on the TUNEL method.
CASPASE ACTIVITY ASSAY
Apoptosis is primarily induced by the activation of caspases. Active caspases recognize a large number of different substrates, leading to the activation of several different apoptotic pathways.
APOPTOSIS MAIN PAGE
Apoptosis, a form of programmed cell death, is not only a major process within normal homeostasis but is present in disease states such as cancer and many autoimmune and neurodegenerative diseases.