Scientific PostersAnalysis of biomarkers in melanoma patients receiving ICI treatments: pre- vs post in responders and progressors
Study of biomarkers of immune-related adverse events and responses in patients treated with immune checkpoint inhibitors may shed light into mechanisms of resistance, T cell exhaustion and other combinatorial therapies. The elevated levels of such biomarkers have potential to predict whether a treatment of PD-1 or PD-1/CTLA-4 antagonist combination will be effective in a certain melanoma patient. Therefore, it may potentially guide healthcare providers to change treatment plans.
Scientific PostersQuickSwitchTM: a validated platform for both screening MHC binding SARS-CoV-2 peptides and making SARS-CoV-2 specific MHC class I and II tetramers
This scientific poster details how QuickSwitch is used to screen peptides for Class I and Class II for SARS-CoV-2.
Scientific PostersA Reversible T Cell Exhaustion-Like In Vitro Assay to Screen Candidate Drugs
The information in this poster describes a T cell differentiation continuum of hierarchial progressive dimunition of effector function.
Scientific PostersHLA-A*02:01 QuickSwitch™ Quant Kit can be used for determining the biological activity of a cancer vaccine
The information in this poster describes our fast and user-friendly assay (QuickSwitch™ Quant) which can help both determine binding of novel peptides to MHC class I molecules and generate new specificity MHC class I tetramers for peptide specific T cell detection.
Scientific PostersRiboCluster Profiler™ Ribo Trap Kit: A novel tool to study regulatory components of mRNA of interest
Post-transcriptional regulation of gene expression plays important roles in most cellular processes such as development and metabolism as well as many diseases such as cancer.
Scientific PostersRiboCluster Profiler™ RIP-Assay Kit for microRNA: A novel immunochemical tool to identify microRNA targets
MicroRNA's (miRNAs) are genomically encoded non-coding RNAs that take part in controlling gene expression. Mature miRNAs are integrated onto RNA-induced silencing complex (RISC) which targets messenger RNA (mRNA) to regulate their translation.
Scientific PostersEstablishment of a Cell Line Visualizing cMyc-Max Interaction
Scientific PostersMetal-Conjugated NeutrAvidin for MHC Multimer Assays Using Mass Cytometry