Reagents for SARS-CoV-2

SARS-CoV-2 is the virus that causes the COVID-19 disease (Coronovirus Disease 2019).  MBLI understands the urgent need to have better understanding and characterization of this disease in order to find treatments and vaccines.  We are continuing to develop and launch new products for the research community as fast as we can.

T-cells are activated only by interacting with processed peptides (e.g. of SARS-CoV-2) that sit in the groove of MHC Class I and II molecules. Identifying these peptides can be used (in forms of peptide-MHC tetramers) to asses vaccine induced immunity and to assist in designing potent vaccines with durable responses. COVID-19 infected cells can be recognized by T-cells only after SARS-CoV-2 peptides are processed and presented in the context of self MHCs. Identifying these peptides has essential utilities:

  • Immune monitoring:  Using peptide-MHC tetramers to assess vaccine-induced immunity
  • Designing potent vaccines that elicit durable responses

MBL International can assist companies and academic investigators who are actively developing coronavirus vaccines with our unique QuickSwitch™ custom tetramer platform.  QuickSwitch™ is a peptide screening plug and play platform that identifies peptides that are more likely to be immunogenic and yet generates corresponding Class I and Class II MHC tetramers.  This platform can identify and validate multi-epitope candidates of SARS-CoV-2 proteins that can potentially elicit for both CD4+ and CD8+ T-cell immune responses. By using MBLI’s MHC tetramer exchange QuickSwitch™ platform for peptide screening, you can identify/validate the binding of predicted peptide sequences of the COVID-19 viral proteins in most common alleles: HLA-A2, A11, A24, A3 and HLA-DR1, DR4, DR15.

We are excited to offer QuickSwitch kit and peptide bundles specifically for SARS-CoV-2 research. Discover more about the kits and peptide sequences in each bundle by clicking the button below:

Product Highlights

MHC Tetramers for COVID-19 Cell Detection

Product CodeClassSequenceTarget
TB-0174-1Class IRLNEVAKNLHLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer
TB-0174-2Class IRLNEVAKNLHLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer
TB-0174-4Class IRLNEVAKNLHLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer
TB-0174-MClass IRLNEVAKNLBiotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer
TB-0174-M2Class IRLNEVAKNLBiotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer
TB-0175-1Class IKLPDDFTGCVHLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer
TB-0175-2Class IKLPDDFTGCVHLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer
TB-0175-4Class IKLPDDFTGCVHLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer
TB-0175-MClass IKLPDDFTGCVBiotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer
TB-0175-M2Class IKLPDDFTGCVBiotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer
TB-0176-1Class IYLQPRTFLLHLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer
TB-0176-2Class IYLQPRTFLLHLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer
TB-0176-4Class IYLQPRTFLLHLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer
TB-0176-MClass IYLQPRTFLLBiotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer
TB-0176-M2Class IYLQPRTFLLBiotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer
TB-0177-1Class IRLQSLQTYVHLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer-
TB-0177-2Class IRLQSLQTYVHLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer-
TB-0177-4Class IRLQSLQTYVHLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer-
TB-0177-MClass IRLQSLQTYVBiotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer
TB-0177-M2Class IRLQSLQTYVBiotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer

Peptides for COVID-19 Research

Product CodeClassSequenceTargetProduct Type
SPC055Class IRLQSLQTYVCOVID-19 spike glycoprotein peptidePeptide
SPC054Class IYLQPRTFLLCOVID-19 spike glycoprotein peptidePeptide
SPC053Class IRLNEVAKNLCOVID-19 spike glycoprotein peptidePeptide
SPC052Class IITQDLFLPFFSNVTWFCOVID-19 chain A spike glycoprotein (51-65)Peptide
SPC051Class IIRVVVLSFELLHAPATCOVID-19 chain A spike glycoprotein (509-523)Peptide
SPC050Class IINRNRFLYIIKLIFLWCOVID-19 membrane glycoprotein (41-55)Peptide
SPC049Class IIMKIILFLALITLATCCOVID-19 ORF7a protein (1-15)Peptide
SPC048Class IILAFVVFLLVTLAILTCOVID-19 envelope protein (21-35)Peptide
SPC047Class IIIWLGFIAGLIAIVMVCOVID-19 surface glycoprotein (1216-1230)Peptide
SPC046Class IIADYSVLYNSASFSTFCOVID-19 chain A spike glycoprotein (363-377)Peptide
SPC045Class IYNYLYRLFCOVID-19 chain A spike glycoprotein (449-456)Peptide
SPC044Class IAAYYVGYLCOVID-19 chain A spike glycoprotein (263-270)Peptide
SPC043Class IITGLYPTLCOVID-19 ORF1ab polyprotein (5573-5580)Peptide
SPC042Class IISDEFSSNVCOVID-19 ORF1ab polyprotein (5583-5591)Peptide
SPC041Class IVTQLYLGGMCOVID-19 ORF1ab polyprotein (5385-5393)Peptide
SPC040Class IKLPDDFTGCVCOVID-19 chain A spike glycoprotein (424-433) PeptidePeptide
SPC039Class ISIIAYTMSLCOVID-19 chain A spike glycoprotein (691-699) PeptidePeptide
SPC038Class IVVFLHVTYVCOVID-19 chain A spike glycoprotein (1060-1068) PeptidePeptide
SPC037Class IGNYNYLYRLCOVID-19 chain A spike glycoprotein (447-455) PeptidePeptide
SPC036Class ISIVRFPNICOVID-19 chain A spike glycoprotein (325-332) PeptidePeptide
SPC035Class IVVLSFELLCOVID-19 chain A spike glycoprotein (511-518) PeptidePeptide
SPC034Class IINITRFQTLCOVID-19 chain A spike glycoprotein (233-241) PeptidePeptide
SPC033Class IMAYRFNGICOVID-19 chain A spike glycoprotein (902-909) PeptidePeptide
SPC032Class IVNFNFNGLCOVID-19 chain A spike glycoprotein (539-546) PeptidePeptide
SPC031Class INYLKRRVVFCOVID-19 ORF1ab (3159-3167)Peptide
SPC030Class IFYGGWHNMLCOVID-19 ORF1ab (4986-4994)Peptide
SPC029Class IDYVYNPFMICOVID-19 ORF1ab (6159-6167)Peptide
SPC028Class ITTIKPVTYKCOVID-19 ORF1ab (1875-1883)Peptide
SPC027Class ISTFNVPMEKCOVID-19 ORF1ab (2600-2608)Peptide
SPC026Class IKTFPPTEPKCOVID-19 nucleocapsid phosphoprotein (362-370)Peptide
SPC025Class IKSAGFPFNKCOVID-19 ORF1ab (4892-4900)Peptide
SPC024Class IASMPTTIAKCOVID-19 ORF1ab (2192-2200)Peptide
SPC023Class IYLYALVYFLCOVID-19 ORF3a protein (107-115)Peptide
SPC022Class IYLNTLTLAVCOVID-19 ORF1ab (6851-6859)Peptide
SPC021Class IYLDAYNMMICOVID-19 ORF1ab (6419-6427)Peptide
SPC020Class ITLMNVLTLVCOVID-19 ORF1ab (3710-3718)Peptide
SPC019Class ISMWALIISVCOVID-19 ORF1ab (3732-3740)Peptide
SPC018Class ILLYDANYFLCOVID-19 ORF3a protein (139-147)Peptide
SPC017Class ILLLDDFVEIICOVID-19 ORF1ab (6749-6758)Peptide
SPC016Class IFLLNKEMYLCOVID-19 ORF1ab (3183-3191)Peptide
SPC015Class IFLAHIQWMVCOVID-19 ORF1ab (3122-3130)Peptide
SPC014Class IIYFTSDYYQLYSTQLSCOVID-19 ORF3a protein (206-220)Peptide
SPC013Class IIWPQIAQFAPSASAFFCOVID-19 nucleocapsid phosphoprotein (301-315)Peptide
SPC012Class IITRFQTLLALHRSYLTCOVID-19 chain A spike glycoprotein (236-250)Peptide
SPC011Class IISEFSSLPSYAAFATACOVID-19 ORF1ab polyprotein (3946-3960)Peptide
SPC010Class IIRAMPNMLRIMASLVLCOVID-19 ORF1ab polyprotein (5016-5030)Peptide
SPC009Class IIMWLSYFIASFRLFARCOVID-19 membrane glycoprotein (91-105)Peptide
SPC008Class IIMDLFMRIFTIGTVTLCOVID-19 ORF3a protein (1-15)Peptide
SPC007Class IILSYYKLGASQRVAGDCOVID-19 membrane glycoprotein (176-190)Peptide
SPC006Class IILLLLDRLNQLESKMSCOVID-19 nucleocapsid phosphoprotein (221-235)Peptide
SPC005Class IILEASFNYLKSPNFSKCOVID-19 ORF1ab polyprotein (2211-2225)Peptide
SPC004Class IIFYVYSRVKNLNSSRVCOVID-19 envelope protein (56-70)Peptide
SPC003Class IIESPFVMMSAPPAQYECOVID-19 ORF1ab polyprotein (1801-1815)Peptide
SPC002Class IIEEIAIILASFSASTSCOVID-19 ORF1ab polyprotein (471-485)Peptide
SPC001Class IIEAFEKMVSLLSVLLSCOVID-19 ORF1ab polyprotein (3906-3920)Peptide

Antibodies for COVID-19 Research

Product CodePRODUCT NAMETargetProduct Type
JM-A2060-50Anti-SARS-CoV-2 Antibody (Clone# 6F10)SARS-CoV-2Antibody
JM-A2061-50Anti-SARS-CoV-2 AntibodySARS-CoV-2Antibody
JM-A2063-100Anti-CoV-2, MERS & SARS-CoV NP Mouse IgG1 AntibodySARS-CoV-2Antibody
JM-A2064-100Anti-CoV-2 & SARS-CoV NP Mouse IgG2b AntibodySARS-CoV-2Antibody
JM-A2065-100Anti-MERS-CoV S1 Mouse IgG1 AntibodySARS-CoV-2Antibody
JM-A2066-100Anti-CoV-2 & SARS-CoV NP Mouse IgG1 AntibodySARS-CoV-2Antibody
JM-A2067-100Anti-MERS-CoV S1 Mouse IgG2a AntibodySARS-CoV-2Antibody
JM-A2068-100Anti-Canine Coronavirus (Self-pair) AntibodySARS-CoV-2Antibody
JM-A2069-100Anti-Canine Coronavirus (Capture) AntibodySARS-CoV-2Antibody
JM-A2070-100Anti-Canine Coronavirus Polyclonal AntibodySARS-CoV-2Antibody
JM-A2072-100Anti-ACE2 AntibodySARS-CoV-2Antibody
JM-A2095-50Anti-SARS-CoV-2 NP Antibody (Clone# 11D5)SARS-CoV-2Antibody
JM-A2093-50Anti-SARS-CoV-2 NP Antibody (Clone# 4G1)SARS-CoV-2Antibody
JM-A2100-100Anti-ANPEP AntibodySARS-CoV-2Antibody
JM-A2103-200Anti-CoV-2 & SARS-CoV S1 Antibody (Clone# CR3022)SARS-CoV-2Antibody
JM-A3000-50Anti-SARS-CoV-2 Spike S1 AntibodySARS-CoV-2Antibody
JM-A3001-50Anti-SARS-CoV-2 Spike S1 Antibody (Clone# 4C7)SARS-CoV-2Antibody

Recombinant Proteins for COVID-19 Research

Product CodePRODUCT NAMETargetProduct Type
JM-P1503-10Recombinant Coronavirus Envelope Protein (SARS-CoV ENV;1-76)SARS-CoV-2Recombinant Protein
JM-P1503-50Recombinant Coronavirus Envelope Protein (SARS-CoV ENV;1-76)SARS-CoV-2Recombinant Protein
JM-P1504-10Recombinant Coronavirus Matrix Protein (SARS-CoV; 182-216)SARS-CoV-2Recombinant Protein
JM-P1504-50Recombinant Coronavirus Matrix Protein (SARS-CoV; 182-216)SARS-CoV-2Recombinant Protein
JM-P1505-10Recombinant Coronavirus Membrane Protein (SARS-CoV, His tag)SARS-CoV-2Recombinant Protein
JM-P1506-10Recombinant Coronavirus Nucleoprotein (CoV-NP 229E)SARS-CoV-2Recombinant Protein
JM-P1506-50Recombinant Coronavirus Nucleoprotein (CoV-NP 229E)SARS-CoV-2Recombinant Protein
JM-P1507-10Recombinant Coronavirus Nucleoprotein (CoV-NP-NL63)SARS-CoV-2Recombinant Protein
JM-P1507-50Recombinant Coronavirus Nucleoprotein (CoV-NP-NL63)SARS-CoV-2Recombinant Protein
JM-P1508-10Recombinant Coronavirus Nucleoprotein (SARS-CoV; 340-390)SARS-CoV-2Recombinant Protein
JM-P1508-50Recombinant Coronavirus Nucleoprotein (SARS-CoV; 340-390)SARS-CoV-2Recombinant Protein
JM-P1509-10Recombinant Coronavirus Nucleoprotein (SARS-CoV)SARS-CoV-2Recombinant Protein
JM-P1510-10Recombinant Coronavirus Nucleoprotein (SARS-CoV; 1-49)SARS-CoV-2Recombinant Protein
JM-P1510-50Recombinant Coronavirus Nucleoprotein (SARS-CoV; 1-49)SARS-CoV-2Recombinant Protein
JM-P1511-10Recombinant Coronavirus Nucleoprotein (SARS-CoV; 1-49, 192-220)SARS-CoV-2Recombinant Protein
JM-P1511-50Recombinant Coronavirus Nucleoprotein (SARS-CoV; 1-49, 192-220)SARS-CoV-2Recombinant Protein
JM-P1512-10Recombinant Coronavirus Nucleoprotein (SARS-CoV; 340-390)SARS-CoV-2Recombinant Protein
JM-P1514-10Recombinant Coronavirus Spike Protein (MERS-CoV S1; 56-295)SARS-CoV-2Recombinant Protein
JM-P1514-50Recombinant Coronavirus Spike Protein (MERS-CoV S1; 56-295)SARS-CoV-2Recombinant Protein
JM-P1515-10Recombinant Coronavirus Spike Protein (SARS-CoV S1; 12-53, 90-115, 171-203)SARS-CoV-2Recombinant Protein
JM-P1515-50Recombinant Coronavirus Spike Protein (SARS-CoV S1; 12-53, 90-115, 171-203)SARS-CoV-2Recombinant Protein
JM-P1516-10Recombinant Coronavirus Spike Protein (SARS-CoV S1; His tag)SARS-CoV-2Recombinant Protein
JM-P1517-10Recombinant Coronavirus Spike Protein (SARS-CoV S2; 408-470, 540-573, His Tag)SARS-CoV-2Recombinant Protein
JM-P1518-10Recombinant Coronavirus Spike Protein (SARS-CoV S2; 408-470, 540-573)SARS-CoV-2Recombinant Protein
JM-P1518-50Recombinant Coronavirus Spike Protein (SARS-CoV S2; 408-470, 540-573)SARS-CoV-2Recombinant Protein
JM-P1519-10Recombinant Coronavirus Spike Protein (SARS-CoV S2)SARS-CoV-2Recombinant Protein
JM-P1519-50Recombinant Coronavirus Spike Protein (SARS-CoV S2)SARS-CoV-2Recombinant Protein
JM-P1520-10Recombinant Coronavirus Spike Protein (SARS-CoV S, His tag)SARS-CoV-2Recombinant Protein
JM-P1523-10Recombinant Coronavirus Nucleoprotein (SARS-CoV-2)SARS-CoV-2Recombinant Protein
JM-P1523-50Recombinant Coronavirus Nucleoprotein (SARS-CoV-2)SARS-CoV-2Recombinant Protein
JM-P1528-10Recombinant Coronavirus Spike Protein (SARS-CoV-2; His tag)SARS-CoV-2Recombinant Protein
JM-P1528-50Recombinant Coronavirus Spike Protein (SARS-CoV-2; His tag)SARS-CoV-2Recombinant Protein
JM-P1533-10Recombinant Coronavirus Spike Protein (SARS-CoV-2; ECD)SARS-CoV-2Recombinant Protein
JM-P1533-50Recombinant Coronavirus Spike Protein (SARS-CoV-2; ECD)SARS-CoV-2Recombinant Protein
JM-P1534-10Recombinant Coronavirus Envelope Protein (SARS-CoV)SARS-CoV-2Recombinant Protein
JM-P1534-50Recombinant Coronavirus Envelope Protein (SARS-CoV)SARS-CoV-2Recombinant Protein
JM-P1536-10Recombinant SARS-CoV-2 Nucleoprotein (1-430, His-tag)SARS-CoV-2Recombinant Protein
JM-P1536-50Recombinant SARS-CoV-2 Nucleoprotein (1-430, His-tag)SARS-CoV-2Recombinant Protein
JM-P1537-10Recombinant SARS-CoV-2 Nucleoprotein (1-430)SARS-CoV-2Recombinant Protein
JM-P1537-50Recombinant SARS-CoV-2 Nucleoprotein (1-430)SARS-CoV-2Recombinant Protein
JM-P1538-10Recombinant SARS-CoV-2 Nucleoprotein (1-430; His-tag)SARS-CoV-2Recombinant Protein
JM-P1538-50Recombinant SARS-CoV-2 Nucleoprotein (1-430; His-tag)SARS-CoV-2Recombinant Protein
JM-P1539-10Recombinant SARS-CoV-2 Nucleoprotein (1-430)SARS-CoV-2Recombinant Protein
JM-P1539-50Recombinant SARS-CoV-2 Nucleoprotein (1-430)SARS-CoV-2Recombinant Protein
JM-P1540-10Recombinant SARS-CoV-2 Spike Protein S1 (His-tag)SARS-CoV-2Recombinant Protein
JM-P1540-50Recombinant SARS-CoV-2 Spike Protein S1 (His-tag)SARS-CoV-2Recombinant Protein
JM-P1541-10Recombinant SARS-CoV-2 Spike Protein S1 (Fc tag)SARS-CoV-2Recombinant Protein
JM-P1541-50Recombinant SARS-CoV-2 Spike Protein S1 (Fc tag)SARS-CoV-2Recombinant Protein

Biochemicals for COVID-19 Research

Product CodePRODUCT NAMETargetProduct Type
JM-B2997-500RemdesivirRemdesivirReagent
JM-B2997-1000RemdesivirRemdesivirReagemt

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COVID-19 Blog

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