Reagents for SARS-CoV-2
SARS-CoV-2 is the virus that causes the COVID-19 disease (Coronovirus Disease 2019). MBLI understands the urgent need to have better understanding and characterization of this disease in order to find treatments and vaccines. We are continuing to develop and launch new products for the research community as fast as we can.
T-cells are activated only by interacting with processed peptides (e.g. of SARS-CoV-2) that sit in the groove of MHC Class I and II molecules. Identifying these peptides can be used (in forms of peptide-MHC tetramers) to asses vaccine induced immunity and to assist in designing potent vaccines with durable responses. COVID-19 infected cells can be recognized by T-cells only after SARS-CoV-2 peptides are processed and presented in the context of self MHCs. Identifying these peptides has essential utilities:
- Immune monitoring: Using peptide-MHC tetramers to assess vaccine-induced immunity
- Designing potent vaccines that elicit durable responses
MBL International can assist companies and academic investigators who are actively developing coronavirus vaccines with our unique QuickSwitch™ custom tetramer platform. QuickSwitch™ is a peptide screening plug and play platform that identifies peptides that are more likely to be immunogenic and yet generates corresponding Class I and Class II MHC tetramers. This platform can identify and validate multi-epitope candidates of SARS-CoV-2 proteins that can potentially elicit for both CD4+ and CD8+ T-cell immune responses. By using MBLI’s MHC tetramer exchange QuickSwitch™ platform for peptide screening, you can identify/validate the binding of predicted peptide sequences of the COVID-19 viral proteins in most common alleles: HLA-A2, A11, A24, A3 and HLA-DR1, DR4, DR15.
We are excited to offer QuickSwitch kit and peptide bundles specifically for SARS-CoV-2 research. Discover more about the kits and peptide sequences in each bundle by clicking the button below:
Product Highlights
MHC Tetramers for COVID-19 Cell Detection
| Product Code | Class | Sequence | Target |
|---|---|---|---|
| TB-0174-1 | Class I | RLNEVAKNL | HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer |
| TB-0174-2 | Class I | RLNEVAKNL | HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer |
| TB-0174-4 | Class I | RLNEVAKNL | HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer |
| TB-0174-M | Class I | RLNEVAKNL | Biotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer |
| TB-0174-M2 | Class I | RLNEVAKNL | Biotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer |
| TB-0175-1 | Class I | KLPDDFTGCV | HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer |
| TB-0175-2 | Class I | KLPDDFTGCV | HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer |
| TB-0175-4 | Class I | KLPDDFTGCV | HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer |
| TB-0175-M | Class I | KLPDDFTGCV | Biotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer |
| TB-0175-M2 | Class I | KLPDDFTGCV | Biotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer |
| TB-0176-1 | Class I | YLQPRTFLL | HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer |
| TB-0176-2 | Class I | YLQPRTFLL | HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer |
| TB-0176-4 | Class I | YLQPRTFLL | HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer |
| TB-0176-M | Class I | YLQPRTFLL | Biotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer |
| TB-0176-M2 | Class I | YLQPRTFLL | Biotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer |
| TB-0177-1 | Class I | RLQSLQTYV | HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer- |
| TB-0177-2 | Class I | RLQSLQTYV | HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer- |
| TB-0177-4 | Class I | RLQSLQTYV | HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Tetramer- |
| TB-0177-M | Class I | RLQSLQTYV | Biotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer |
| TB-0177-M2 | Class I | RLQSLQTYV | Biotinylated HLA-A*02:01 SARS-CoV-2 Spike Glycoprotein Monomer |
Peptides for COVID-19 Research
| Product Code | Class | Sequence | Target | Product Type |
|---|---|---|---|---|
| SPC055 | Class I | RLQSLQTYV | COVID-19 spike glycoprotein peptide | Peptide |
| SPC054 | Class I | YLQPRTFLL | COVID-19 spike glycoprotein peptide | Peptide |
| SPC053 | Class I | RLNEVAKNL | COVID-19 spike glycoprotein peptide | Peptide |
| SPC052 | Class II | TQDLFLPFFSNVTWF | COVID-19 chain A spike glycoprotein (51-65) | Peptide |
| SPC051 | Class II | RVVVLSFELLHAPAT | COVID-19 chain A spike glycoprotein (509-523) | Peptide |
| SPC050 | Class II | NRNRFLYIIKLIFLW | COVID-19 membrane glycoprotein (41-55) | Peptide |
| SPC049 | Class II | MKIILFLALITLATC | COVID-19 ORF7a protein (1-15) | Peptide |
| SPC048 | Class II | LAFVVFLLVTLAILT | COVID-19 envelope protein (21-35) | Peptide |
| SPC047 | Class II | IWLGFIAGLIAIVMV | COVID-19 surface glycoprotein (1216-1230) | Peptide |
| SPC046 | Class II | ADYSVLYNSASFSTF | COVID-19 chain A spike glycoprotein (363-377) | Peptide |
| SPC045 | Class I | YNYLYRLF | COVID-19 chain A spike glycoprotein (449-456) | Peptide |
| SPC044 | Class I | AAYYVGYL | COVID-19 chain A spike glycoprotein (263-270) | Peptide |
| SPC043 | Class I | ITGLYPTL | COVID-19 ORF1ab polyprotein (5573-5580) | Peptide |
| SPC042 | Class I | ISDEFSSNV | COVID-19 ORF1ab polyprotein (5583-5591) | Peptide |
| SPC041 | Class I | VTQLYLGGM | COVID-19 ORF1ab polyprotein (5385-5393) | Peptide |
| SPC040 | Class I | KLPDDFTGCV | COVID-19 chain A spike glycoprotein (424-433) Peptide | Peptide |
| SPC039 | Class I | SIIAYTMSL | COVID-19 chain A spike glycoprotein (691-699) Peptide | Peptide |
| SPC038 | Class I | VVFLHVTYV | COVID-19 chain A spike glycoprotein (1060-1068) Peptide | Peptide |
| SPC037 | Class I | GNYNYLYRL | COVID-19 chain A spike glycoprotein (447-455) Peptide | Peptide |
| SPC036 | Class I | SIVRFPNI | COVID-19 chain A spike glycoprotein (325-332) Peptide | Peptide |
| SPC035 | Class I | VVLSFELL | COVID-19 chain A spike glycoprotein (511-518) Peptide | Peptide |
| SPC034 | Class I | INITRFQTL | COVID-19 chain A spike glycoprotein (233-241) Peptide | Peptide |
| SPC033 | Class I | MAYRFNGI | COVID-19 chain A spike glycoprotein (902-909) Peptide | Peptide |
| SPC032 | Class I | VNFNFNGL | COVID-19 chain A spike glycoprotein (539-546) Peptide | Peptide |
| SPC031 | Class I | NYLKRRVVF | COVID-19 ORF1ab (3159-3167) | Peptide |
| SPC030 | Class I | FYGGWHNML | COVID-19 ORF1ab (4986-4994) | Peptide |
| SPC029 | Class I | DYVYNPFMI | COVID-19 ORF1ab (6159-6167) | Peptide |
| SPC028 | Class I | TTIKPVTYK | COVID-19 ORF1ab (1875-1883) | Peptide |
| SPC027 | Class I | STFNVPMEK | COVID-19 ORF1ab (2600-2608) | Peptide |
| SPC026 | Class I | KTFPPTEPK | COVID-19 nucleocapsid phosphoprotein (362-370) | Peptide |
| SPC025 | Class I | KSAGFPFNK | COVID-19 ORF1ab (4892-4900) | Peptide |
| SPC024 | Class I | ASMPTTIAK | COVID-19 ORF1ab (2192-2200) | Peptide |
| SPC023 | Class I | YLYALVYFL | COVID-19 ORF3a protein (107-115) | Peptide |
| SPC022 | Class I | YLNTLTLAV | COVID-19 ORF1ab (6851-6859) | Peptide |
| SPC021 | Class I | YLDAYNMMI | COVID-19 ORF1ab (6419-6427) | Peptide |
| SPC020 | Class I | TLMNVLTLV | COVID-19 ORF1ab (3710-3718) | Peptide |
| SPC019 | Class I | SMWALIISV | COVID-19 ORF1ab (3732-3740) | Peptide |
| SPC018 | Class I | LLYDANYFL | COVID-19 ORF3a protein (139-147) | Peptide |
| SPC017 | Class I | LLLDDFVEII | COVID-19 ORF1ab (6749-6758) | Peptide |
| SPC016 | Class I | FLLNKEMYL | COVID-19 ORF1ab (3183-3191) | Peptide |
| SPC015 | Class I | FLAHIQWMV | COVID-19 ORF1ab (3122-3130) | Peptide |
| SPC014 | Class II | YFTSDYYQLYSTQLS | COVID-19 ORF3a protein (206-220) | Peptide |
| SPC013 | Class II | WPQIAQFAPSASAFF | COVID-19 nucleocapsid phosphoprotein (301-315) | Peptide |
| SPC012 | Class II | TRFQTLLALHRSYLT | COVID-19 chain A spike glycoprotein (236-250) | Peptide |
| SPC011 | Class II | SEFSSLPSYAAFATA | COVID-19 ORF1ab polyprotein (3946-3960) | Peptide |
| SPC010 | Class II | RAMPNMLRIMASLVL | COVID-19 ORF1ab polyprotein (5016-5030) | Peptide |
| SPC009 | Class II | MWLSYFIASFRLFAR | COVID-19 membrane glycoprotein (91-105) | Peptide |
| SPC008 | Class II | MDLFMRIFTIGTVTL | COVID-19 ORF3a protein (1-15) | Peptide |
| SPC007 | Class II | LSYYKLGASQRVAGD | COVID-19 membrane glycoprotein (176-190) | Peptide |
| SPC006 | Class II | LLLLDRLNQLESKMS | COVID-19 nucleocapsid phosphoprotein (221-235) | Peptide |
| SPC005 | Class II | LEASFNYLKSPNFSK | COVID-19 ORF1ab polyprotein (2211-2225) | Peptide |
| SPC004 | Class II | FYVYSRVKNLNSSRV | COVID-19 envelope protein (56-70) | Peptide |
| SPC003 | Class II | ESPFVMMSAPPAQYE | COVID-19 ORF1ab polyprotein (1801-1815) | Peptide |
| SPC002 | Class II | EEIAIILASFSASTS | COVID-19 ORF1ab polyprotein (471-485) | Peptide |
| SPC001 | Class II | EAFEKMVSLLSVLLS | COVID-19 ORF1ab polyprotein (3906-3920) | Peptide |
Antibodies for COVID-19 Research
| Product Code | PRODUCT NAME | Target | Product Type |
|---|---|---|---|
| JM-A2060-50 | Anti-SARS-CoV-2 Antibody (Clone# 6F10) | SARS-CoV-2 | Antibody |
| JM-A2061-50 | Anti-SARS-CoV-2 Antibody | SARS-CoV-2 | Antibody |
| JM-A2063-100 | Anti-CoV-2, MERS & SARS-CoV NP Mouse IgG1 Antibody | SARS-CoV-2 | Antibody |
| JM-A2064-100 | Anti-CoV-2 & SARS-CoV NP Mouse IgG2b Antibody | SARS-CoV-2 | Antibody |
| JM-A2065-100 | Anti-MERS-CoV S1 Mouse IgG1 Antibody | SARS-CoV-2 | Antibody |
| JM-A2066-100 | Anti-CoV-2 & SARS-CoV NP Mouse IgG1 Antibody | SARS-CoV-2 | Antibody |
| JM-A2067-100 | Anti-MERS-CoV S1 Mouse IgG2a Antibody | SARS-CoV-2 | Antibody |
| JM-A2068-100 | Anti-Canine Coronavirus (Self-pair) Antibody | SARS-CoV-2 | Antibody |
| JM-A2069-100 | Anti-Canine Coronavirus (Capture) Antibody | SARS-CoV-2 | Antibody |
| JM-A2070-100 | Anti-Canine Coronavirus Polyclonal Antibody | SARS-CoV-2 | Antibody |
| JM-A2072-100 | Anti-ACE2 Antibody | SARS-CoV-2 | Antibody |
| JM-A2095-50 | Anti-SARS-CoV-2 NP Antibody (Clone# 11D5) | SARS-CoV-2 | Antibody |
| JM-A2093-50 | Anti-SARS-CoV-2 NP Antibody (Clone# 4G1) | SARS-CoV-2 | Antibody |
| JM-A2100-100 | Anti-ANPEP Antibody | SARS-CoV-2 | Antibody |
| JM-A2103-200 | Anti-CoV-2 & SARS-CoV S1 Antibody (Clone# CR3022) | SARS-CoV-2 | Antibody |
| JM-A3000-50 | Anti-SARS-CoV-2 Spike S1 Antibody | SARS-CoV-2 | Antibody |
| JM-A3001-50 | Anti-SARS-CoV-2 Spike S1 Antibody (Clone# 4C7) | SARS-CoV-2 | Antibody |
Recombinant Proteins for COVID-19 Research
| Product Code | PRODUCT NAME | Target | Product Type |
|---|---|---|---|
| JM-P1503-10 | Recombinant Coronavirus Envelope Protein (SARS-CoV ENV;1-76) | SARS-CoV-2 | Recombinant Protein |
| JM-P1503-50 | Recombinant Coronavirus Envelope Protein (SARS-CoV ENV;1-76) | SARS-CoV-2 | Recombinant Protein |
| JM-P1504-10 | Recombinant Coronavirus Matrix Protein (SARS-CoV; 182-216) | SARS-CoV-2 | Recombinant Protein |
| JM-P1504-50 | Recombinant Coronavirus Matrix Protein (SARS-CoV; 182-216) | SARS-CoV-2 | Recombinant Protein |
| JM-P1505-10 | Recombinant Coronavirus Membrane Protein (SARS-CoV, His tag) | SARS-CoV-2 | Recombinant Protein |
| JM-P1506-10 | Recombinant Coronavirus Nucleoprotein (CoV-NP 229E) | SARS-CoV-2 | Recombinant Protein |
| JM-P1506-50 | Recombinant Coronavirus Nucleoprotein (CoV-NP 229E) | SARS-CoV-2 | Recombinant Protein |
| JM-P1507-10 | Recombinant Coronavirus Nucleoprotein (CoV-NP-NL63) | SARS-CoV-2 | Recombinant Protein |
| JM-P1507-50 | Recombinant Coronavirus Nucleoprotein (CoV-NP-NL63) | SARS-CoV-2 | Recombinant Protein |
| JM-P1508-10 | Recombinant Coronavirus Nucleoprotein (SARS-CoV; 340-390) | SARS-CoV-2 | Recombinant Protein |
| JM-P1508-50 | Recombinant Coronavirus Nucleoprotein (SARS-CoV; 340-390) | SARS-CoV-2 | Recombinant Protein |
| JM-P1509-10 | Recombinant Coronavirus Nucleoprotein (SARS-CoV) | SARS-CoV-2 | Recombinant Protein |
| JM-P1510-10 | Recombinant Coronavirus Nucleoprotein (SARS-CoV; 1-49) | SARS-CoV-2 | Recombinant Protein |
| JM-P1510-50 | Recombinant Coronavirus Nucleoprotein (SARS-CoV; 1-49) | SARS-CoV-2 | Recombinant Protein |
| JM-P1511-10 | Recombinant Coronavirus Nucleoprotein (SARS-CoV; 1-49, 192-220) | SARS-CoV-2 | Recombinant Protein |
| JM-P1511-50 | Recombinant Coronavirus Nucleoprotein (SARS-CoV; 1-49, 192-220) | SARS-CoV-2 | Recombinant Protein |
| JM-P1512-10 | Recombinant Coronavirus Nucleoprotein (SARS-CoV; 340-390) | SARS-CoV-2 | Recombinant Protein |
| JM-P1514-10 | Recombinant Coronavirus Spike Protein (MERS-CoV S1; 56-295) | SARS-CoV-2 | Recombinant Protein |
| JM-P1514-50 | Recombinant Coronavirus Spike Protein (MERS-CoV S1; 56-295) | SARS-CoV-2 | Recombinant Protein |
| JM-P1515-10 | Recombinant Coronavirus Spike Protein (SARS-CoV S1; 12-53, 90-115, 171-203) | SARS-CoV-2 | Recombinant Protein |
| JM-P1515-50 | Recombinant Coronavirus Spike Protein (SARS-CoV S1; 12-53, 90-115, 171-203) | SARS-CoV-2 | Recombinant Protein |
| JM-P1516-10 | Recombinant Coronavirus Spike Protein (SARS-CoV S1; His tag) | SARS-CoV-2 | Recombinant Protein |
| JM-P1517-10 | Recombinant Coronavirus Spike Protein (SARS-CoV S2; 408-470, 540-573, His Tag) | SARS-CoV-2 | Recombinant Protein |
| JM-P1518-10 | Recombinant Coronavirus Spike Protein (SARS-CoV S2; 408-470, 540-573) | SARS-CoV-2 | Recombinant Protein |
| JM-P1518-50 | Recombinant Coronavirus Spike Protein (SARS-CoV S2; 408-470, 540-573) | SARS-CoV-2 | Recombinant Protein |
| JM-P1519-10 | Recombinant Coronavirus Spike Protein (SARS-CoV S2) | SARS-CoV-2 | Recombinant Protein |
| JM-P1519-50 | Recombinant Coronavirus Spike Protein (SARS-CoV S2) | SARS-CoV-2 | Recombinant Protein |
| JM-P1520-10 | Recombinant Coronavirus Spike Protein (SARS-CoV S, His tag) | SARS-CoV-2 | Recombinant Protein |
| JM-P1523-10 | Recombinant Coronavirus Nucleoprotein (SARS-CoV-2) | SARS-CoV-2 | Recombinant Protein |
| JM-P1523-50 | Recombinant Coronavirus Nucleoprotein (SARS-CoV-2) | SARS-CoV-2 | Recombinant Protein |
| JM-P1528-10 | Recombinant Coronavirus Spike Protein (SARS-CoV-2; His tag) | SARS-CoV-2 | Recombinant Protein |
| JM-P1528-50 | Recombinant Coronavirus Spike Protein (SARS-CoV-2; His tag) | SARS-CoV-2 | Recombinant Protein |
| JM-P1533-10 | Recombinant Coronavirus Spike Protein (SARS-CoV-2; ECD) | SARS-CoV-2 | Recombinant Protein |
| JM-P1533-50 | Recombinant Coronavirus Spike Protein (SARS-CoV-2; ECD) | SARS-CoV-2 | Recombinant Protein |
| JM-P1534-10 | Recombinant Coronavirus Envelope Protein (SARS-CoV) | SARS-CoV-2 | Recombinant Protein |
| JM-P1534-50 | Recombinant Coronavirus Envelope Protein (SARS-CoV) | SARS-CoV-2 | Recombinant Protein |
| JM-P1536-10 | Recombinant SARS-CoV-2 Nucleoprotein (1-430, His-tag) | SARS-CoV-2 | Recombinant Protein |
| JM-P1536-50 | Recombinant SARS-CoV-2 Nucleoprotein (1-430, His-tag) | SARS-CoV-2 | Recombinant Protein |
| JM-P1537-10 | Recombinant SARS-CoV-2 Nucleoprotein (1-430) | SARS-CoV-2 | Recombinant Protein |
| JM-P1537-50 | Recombinant SARS-CoV-2 Nucleoprotein (1-430) | SARS-CoV-2 | Recombinant Protein |
| JM-P1538-10 | Recombinant SARS-CoV-2 Nucleoprotein (1-430; His-tag) | SARS-CoV-2 | Recombinant Protein |
| JM-P1538-50 | Recombinant SARS-CoV-2 Nucleoprotein (1-430; His-tag) | SARS-CoV-2 | Recombinant Protein |
| JM-P1539-10 | Recombinant SARS-CoV-2 Nucleoprotein (1-430) | SARS-CoV-2 | Recombinant Protein |
| JM-P1539-50 | Recombinant SARS-CoV-2 Nucleoprotein (1-430) | SARS-CoV-2 | Recombinant Protein |
| JM-P1540-10 | Recombinant SARS-CoV-2 Spike Protein S1 (His-tag) | SARS-CoV-2 | Recombinant Protein |
| JM-P1540-50 | Recombinant SARS-CoV-2 Spike Protein S1 (His-tag) | SARS-CoV-2 | Recombinant Protein |
| JM-P1541-10 | Recombinant SARS-CoV-2 Spike Protein S1 (Fc tag) | SARS-CoV-2 | Recombinant Protein |
| JM-P1541-50 | Recombinant SARS-CoV-2 Spike Protein S1 (Fc tag) | SARS-CoV-2 | Recombinant Protein |
Biochemicals for COVID-19 Research
| Product Code | PRODUCT NAME | Target | Product Type |
|---|---|---|---|
| JM-B2997-500 | Remdesivir | Remdesivir | Reagent |
| JM-B2997-1000 | Remdesivir | Remdesivir | Reagemt |
Learn more about COVID-19 by reading our blog post
Contact us today if you have specific needs that you do not see listed here. We’re here to help advance your COVID-19 research.
