T-Select I-Ab OVA 323-339 Tetramer-APC
Specifications:
Description
MHC Tetramers are used for the detection of antigen-specific T-cell populations. MHC-peptide tetramer complexes recognize antigen specific T-cells at the single cell level, allowing for accurate measurements of the functional immune response in cancer, infectious diseases, and autoimmune diseases. Due to their increased avidity, MHC tetramers stably bind to cognate TcRs and are evaluated using flow cytometry.
| Target: | OVA |
|---|---|
| Product Type: | Tetramer |
| Size: | 20 Tests |
| Application: | FCM |
| Research Area / Disease: | Immune Monitoring, Immunology |
| Class: | Class II |
| Allele: | I-Ab |
| Peptide Sequence: | ISQAVHAAHAEINEAGR |
| Conjugate: | APC |
| Species Reactivity: | Mouse |
| Specificity: | OVA |
| Storage Temperature: | 4°C |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
Citations
- Tian D et al. Double negative T cells mediate Lag3-dependent antigen-specific protection in allergic asthma. Nat Commun. 10, 4246 (2019)
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