Products MHC Tetramers & Monomers MHC Tetramers MHC Class II T-Select I-Ab OVA 323-339 Tetramer-PE

T-Select I-Ab OVA 323-339 Tetramer-PE

Specifications:

Description

MHC Tetramers are used for the detection of antigen-specific T-cell populations. MHC-peptide tetramer complexes recognize antigen specific T-cells at the single cell level, allowing for accurate measurements of the functional immune response in cancer, infectious diseases, and autoimmune diseases. Due to their increased avidity, MHC tetramers stably bind to cognate TcRs and are evaluated using flow cytometry.

Target:	OVA
Product Type:	Tetramer
Size:	20 Tests
Application:	FCM
Research Area / Disease:	Immune Monitoring, Immunology
Class:	Class II
Allele:	I-Ab
Peptide Sequence:	ISQAVHAAHAEINEAGR
Conjugate:	PE
Species Reactivity:	Mouse
Specificity:	OVA

Citations

Tian D et al. Double negative T cells mediate Lag3-dependent antigen-specific protection in allergic asthma. Nat Commun. 10, 4246 (2019)
Sonner JK et al. Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology. Nat Commun. 10, 4877 (2019)