I-Ab ESAT-6 1-20 Tetramer-PE

Specifications:

Description

MHC Tetramers are used for the detection of antigen-specific T-cell populations. MHC-peptide tetramer complexes recognize antigen specific T-cells at the single cell level, allowing for accurate measurements of the functional immune response in cancer, infectious diseases, and autoimmune diseases.  Due to their increased avidity, MHC tetramers stably bind to cognate TcRs and are evaluated using flow cytometry.

Target: TB
Product Type: Tetramer
Size: 20 Tests
Application: FCM
Research Area / Disease: Immune Monitoring, Immunology
Class: Class II
Allele: I-Ab
Peptide Sequence: MTEQQWNFAGIEAAASAIQG
Conjugate: PE
Species Reactivity: Mouse
Specificity: ESAT-6
Storage Temperature: 4°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Citations

  1. Liao T-YA, et al. PLoS ONE 10: e0145833 (2015, MBL)

References

  1. Kubota, H., et al., J. Immunol. 145, 3924-3931 (1990)
  2. Hans et al, GWAS_Supplementary Information
  3. Asthma GWAS paper_Nat Comm