H-2Ld MuLV gp70 Tetramer-SPSYVYHQF-PE



MHC Tetramers are used for the detection of antigen-specific T-cell populations. MHC-peptide tetramer complexes recognize antigen specific T-cells at the single cell level, allowing for accurate measurements of the functional immune response in cancer, infectious diseases, and autoimmune diseases.  Due to their increased avidity, MHC tetramers stably bind to cognate TcRs and are evaluated using flow cytometry.

Target: MuLV
Product Type: Tetramer
Size: 50 tests
Application: FCM
Research Area / Disease: Immune Monitoring, Immunology
Class: Class I
Allele: H-2Ld
Peptide Sequence: SPSYVYHQF
Conjugate: PE
Species Reactivity: Mouse
Specificity: gp70
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.


Zhang, L., Jiang, L., Yu, L. et al. Inhibition of UBA6 by inosine augments tumour immunogenicity and responses. Nat Commun 13, 5413 (2022). https://doi.org/10.1038/s41467-022-33116-z

Agarwal, Yash, et al. “Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity.” Nature Biomedical Engineering 6.2 (2022): 129-143.

Zúñiga, Luis Alejandro, et al. “Intratumoral delivery of TransCon™ TLR7/8 Agonist promotes sustained anti-tumor activity and local immune cell activation while minimizing systemic cytokine induction.” Cancer Cell International 22.1 (2022): 1-17.

Herrador-Cañete, Guillermo, et al. “Galectin-3 inhibition boosts the therapeutic efficacy of Semliki Forest virus in pediatric osteosarcoma.” Molecular Therapy-Oncolytics 26 (2022): 246-264.

Sivick KE et al. Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity. Cell Rep. 25, 3074-3085.e5 (2018)

Code TB-M521-1
Product Type Tetramer
Size 50 tests
Application FCM