Tetramer/BV421 – H-2 Db Gp 100 (KVPRNQDWL)

Specifications:

Description

MHC Tetramers are used for the detection of antigen-specific T-cell populations. MHC-peptide tetramer complexes recognize antigen specific T-cells at the single cell level, allowing for accurate measurements of the functional immune response in cancer, infectious diseases, and autoimmune diseases.  Due to their increased avidity, MHC tetramers stably bind to cognate TcRs and are evaluated using flow cytometry.

Target: Cancer/Melanoma
Product Type: Tetramer
Size: 50 tests
Application: FCM
Research Area / Disease: Immune Monitoring, Immunology
Class: Class I
Allele: H-2Db
Peptide Sequence: KVPRNQDWL
Conjugate: BV421
Species Reactivity: Mouse
Specificity: gp100
Storage Temperature: 4°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

References

  1. Kubota, H., et al., J. Immunol. 145, 3924-3931 (1990)
  2. Hans et al, GWAS_Supplementary Information
  3. Asthma GWAS paper_Nat Comm