QuickSwitch™ Quant HLA-A*03:01 Tetramer Kit-PE
Specifications:
Background
This QuickSwitch Starter Guide shows how to use our QuickSwitch kits with clear illustrations and step by step directions.
Contact us with any specific questions you may have!
Components
- Tetramer with an irrelevant exchangeable peptide in the MHC groove
- A peptide exchange factor for catalyzing the peptide exchange reaction
- A high affinity MHC-binding reference peptide used as peptide exchange positive control
- Magnetic beads conjugated with anti MHC antibody for tetramer capture
- An Assay Buffer for diluting reagents and washing steps
Description
QuickSwitch™ Tetramer Kit utilizes a patented technique for exchanging up to ten peptides on an MHC class I tetramer. Reduce time and cost with this kit to create your own custom tetramers. The resulting custom tetramers can be used for multiple applications, including screening immunogenic peptides.
| Target: | Custom |
|---|---|
| Product Type: | Tetramer |
| Size: | 25 µg |
| Application: | FCM |
| Research Area / Disease: | Immune Monitoring, Immunology |
| Class: | Class I |
| Allele: | HLA-A*03:01 |
| Peptide Sequence: | Custom |
| Conjugate: | PE |
| Species Reactivity: | Human |
| Specificity: | Custom |
Citations
Kula, T., Dezfulian, M. H., Wang, C. I., Abdelfattah, N. S., Hartman, Z. C., Wucherpfennig, K. W., … Elledge, S. J. (2019). T-Scan: A Genome-wide Method for the Systematic Discovery of T Cell Epitopes. Cell, 178(4). DOI: 10.1016/j.cell.2019.07.009
References
- Kubota, H., et al., J. Immunol. 145, 3924-3931 (1990)
- Hans et al, GWAS_Supplementary Information
- Asthma GWAS paper_Nat Comm
