QuickSwitch™ Quant HLA-A*02:01 Tetramer Kit-BV421

Specifications:

Background

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Description

QuickSwitch™ Tetramer Kit utilizes a patented technique for exchanging up to ten peptides on an MHC class I tetramer. Reduce time and cost with this kit to create your own custom tetramers.  The resulting custom tetramers can be used for multiple applications, including screening immunogenic peptides.

Target: Custom
Product Type: Tetramer
Size: 1 kit
Application: FCM
Research Area / Disease: Immune Monitoring, Immunology
Class: Class I
Allele: HLA-A*02:01
Peptide Sequence: Custom
Conjugate: BV421
Species Reactivity: Human
Specificity: Custom
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Citations

Zhang, Y., Zhang, J., Chen, Y., Luo, B., Yuan, Y., Huang, F., . . . Zhang, H. (2020). The ORF8 Protein of SARS-CoV-2 Mediates Immune Evasion through Potently Downregulating MHC-I. Biorxiv. doi:10.1101/2020.05.24.111823

Lo, W., Parkhurst, M., Robbins, P. F., Tran, E., Lu, Y., Jia, L., . . . Rosenberg, S. A. (2019). Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer. Cancer Immunology Research, 7(4), 534-543. doi:10.1158/2326-6066.cir-18-0686

Poluektov, Y., Daftarian, P., & Delcommenne, M. C. (2020). Assessment of SARS-CoV-2 Specific CD4( ) and CD8 ( ) T Cell Responses Using MHC Class I and II Tetramers. Biorxiv. doi:10.1101/2020.07.08.194209

Dustin, M. L., & Mayya, V. (2019). Faculty Opinions recommendation of T-Scan: A Genome-wide Method for the Systematic Discovery of T Cell Epitopes. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature. doi:10.3410/f.736361281.793566682