HLA-A*02:01 EBV LMP1 Tetramer-YLLEMLWRL-PE

Specifications:

Description

MHC Tetramers are used for the detection of antigen-specific T-cell populations. MHC-peptide tetramer complexes recognize antigen specific T-cells at the single cell level, allowing for accurate measurements of the functional immune response in cancer, infectious diseases, and autoimmune diseases.  Due to their increased avidity, MHC tetramers stably bind to cognate TcRs and are evaluated using flow cytometry.

Target: EBV
Product Type: Tetramer
Size: 50 ug
Application: FCM
Research Area / Disease: Immune Monitoring, Immunology
Class: Class I
Allele: HLA-A*02:01
Peptide Sequence: LMP1
Conjugate: PE
Species Reactivity: Human
Specificity: LMP1
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Citations

  1. Kobayashi E, et al. Nature Med 19: 1542–1546 (2013)
  2. Shultz LD, et al. PNAS 107: 13022-13027 (2010)

References

  1. Kubota, H., et al., J. Immunol. 145, 3924-3931 (1990)
  2. Hans et al, GWAS_Supplementary Information
  3. Asthma GWAS paper_Nat Comm