iTAg Tetramer/APC – HLA-A*02:01 gp100 (IMDQVPFSV)
MHC Tetramers are used for the detection of antigen-specific T-cell populations. MHC-peptide tetramer complexes recognize antigen specific T-cells at the single cell level, allowing for accurate measurements of the functional immune response in cancer, infectious diseases, and autoimmune diseases. Due to their increased avidity, MHC tetramers stably bind to cognate TcRs and are evaluated using flow cytometry.
|Research Area / Disease:||Immune Monitoring, Immunology|
|Regulatory Statement:||For Research Use Only. Not for use in diagnostic procedures.|
- Walker EB, et al., Clin Cancer Res 15: 2541-2551 (2009)