iTAg Tetramer/APC – HLA-A*02:01 Influenza-M1 (GILGFVFTL)

Specifications:

Description

MHC Tetramers are used for the detection of antigen-specific T-cell populations. MHC-peptide tetramer complexes recognize antigen specific T-cells at the single cell level, allowing for accurate measurements of the functional immune response in cancer, infectious diseases, and autoimmune diseases.  Due to their increased avidity, MHC tetramers stably bind to cognate TcRs and are evaluated using flow cytometry.

Target: Influenza
Product Type: Tetramer
Size: 50 tests
Application: FCM
Research Area / Disease: Immune Monitoring, Immunology
Class: Class I
Allele: HLA-A*02:01
Peptide Sequence: GILGFVFTL
Conjugate: APC
Species Reactivity: Human
Specificity: M1
Storage Temperature: 4°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Citations

  1. Paczesny S, et al. J Exp Med 199: 1503-1511 (2004 BCI)
  2. Akiyama Y, et al. J. Transl. Med. 3: 4-13 (2005)
  3. Wong RM, et al. Int Immunol 19: 1223-1234 (2007 BCI)
  4. Walker EB, et al. Clin. Cancer Res 14: 5270-5283 (2008 BCI)
  5. Frleta D, et al. J. Immunol 182: 2766-2776 (2009 BCI)
  6. Romano E, et al. Clin. Cancer Res 17: 1984-1997 (2011 BCI) Mantovani S, et al. J Immunol 169: 6253-6260 (2002 BCI)
  7. Aandahl EM. et al. J. Immunol. 170: 2349-2355 (2003 BCI)
  8. Paczesny S, et al. J Exp Med 199: 1503-1511 (2004 BCI)
  9. Coughlin CM, et al. Blood 103: 2046-2054 (2004 BCI)
  10. Hess C, et al. Blood 104: 3463-3471 (2004 BCI)
  11. Aandahl EM, et al. Blood 104: 3672-3678 (2004 BCI)
  12. Akiyama Y, et al. J. Transl. Med. 3: 4-13 (2005)
  13. Moran TP, et al. J Immunol 175: 3431-3438 (2005 BCI)
  14. Cooper LJN, et al. Blood 105: 1622-1631 (2005 BCI)
  15. Yang S, et al. Clin Cancer Res 11: 5603-5615 (2005 BCI)
  16. Naumov YN, et al. J Immunol 177: 2006-2014 (2006 BCI)
  17. Casati C. et al. Cancer Res. 66: 4450-4460 (2006 BCI)
  18. Zhang H, et al. J Immunol 179: 4910-4918 (2007 BCI)
  19. Naumov YN, et al. J Immunol 181: 7407-7419 (2008)
  20. Walker EB, et al. Clin. Cancer Res 14: 5270-5283 (2008 BCI)
  21. He X-S, et al. J Infect Dis 197: 803-811 (2008 BCI)
  22. Yu CI, et al. Blood 112: 3671-3678 (2008 BCI)
  23. Turtle CJ, et al. Immunity 31: 834-844 (2009 BCI)
  24. Frleta D, et al. J. Immunol 182: 2766-2776 (2009 BCI)
  25. Harari A, et al. J Virol 83: 2862-2871 (2009 BCI)
  26. Cellerai C, et al. J Virol 84: 3868–3878 (2010 BCI)
  27. Tu W, et al. J Virol 84: 6527-6535 (2010 BCI)
  28. Ndhlovu ZM, et al. PNAS 107: 3669-3674 (2010 BCI)
  29. Alanio C, et al. Blood 115: 3718-3725 (2010 BCI)
  30. Romano E, et al. Clin Cancer Res 17: 1984-1997 (2011 BCI)
  31. Odumade OA, et al. J Exp Med 209: 471-478 (2012 BCI)
  32. Flamar A-L, et al.J Immunol 189: 2645-2655 (2012 BCI)
  33. Bruns H, et al. Clin Cancer Res 21: 2075-2083 (2015, BCI)

References

  1. Kubota, H., et al., J. Immunol. 145, 3924-3931 (1990)
  2. Hans et al, GWAS_Supplementary Information
  3. Asthma GWAS paper_Nat Comm