Anti-Fas (CD95) mAb (Monoclonal Antibody)

Fas Monoclonal Antibody.

Specifications:

Description

Monoclonal Antibody of 100 µl targeting Fas for FCM, WB.

Target: Fas
Product Type: Antibody
Size: 100 µl
Application: FCM, WB
Research Area / Disease: Apoptosis
Conjugate: Unlabeled
Antibody Type: Monoclonal
Clone Number: CH-11
Formulation: 0.5 mg/mL in PBS/50% glycerol, pH 7.2
Isotype: IgM
Immunogen: FS-7 Human diploid fibroblasts
Host Species: Mouse
Species Reactivity: Human
Source: This antibody was purified from ascites fluid using affinity chromatography. This hybridoma (clone CH-11) was established by fusion of mouse myeloma cell NS-1 with Balb/c mouse splenocyte immunized with the human diploid fibroblast FS-7 cell lin E.
Reactivity: This antibody induces apoptosis in human cell lines expressing Fas antigen
Gene ID Human:

355

Gene ID Mouse:

14102

Storage Temperature: -20°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Citations

  1. Murthy A et al. A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3. Nature 506, 456-62 (2014),
  2. Zanin-Zhorov A et al. Fibronectin-associated Fas ligand rapidly induces opposing and time-dependent effects on the activation and apoptosis of T cells. J Immunol. 171, 5882-9 (2003)
  3. Yamaji, T., et al., J. Biol. Chem. 285, 35505-35518 (2010)
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  9. Kotone-Miyahara, Y., et al., J. Leukoc. Biol. 76, 1047-1056 (2004)
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  11. Ichikawa, K., et al., Int. Immunol. 12, 555-562 (2000)
  12. Tsukumo, S. I., et al., Genes Cells 4, 541-549 (1999)
  13. Yamashita, K., et al., Blood 93, 674-685 (1999)
  14. Ito, N., et al., Cell 66, 233-243 (1991)
  15. Kobayashi, N., et al., PNAS 87, 9620-9624 (1990)
  16. Yonehara, S., et al., J. Exp. Med. 169, 1747-1756 (1989)
  17. Kozako T et al. Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines. BMC Cancer. 18, 791 (2018)
  18. Jing ZT et al. Hepatitis B Virus Surface Antigen Enhances the Sensitivity of Hepatocytes to Fas-Mediated Apoptosis via Suppression of AKT Phosphorylation. J Immunol. 201, 2303-2314 (2018)
Code SY-001
Product Type Antibody
Size 100 µl
Application FCM, WB
Price
$350.89
Qty:

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