Anti-IGF2BP3 (IMP3) (Human/Mouse) pAb (Polyclonal Antibody)
IGF2BP3/IMP3 Polyclonal Antibody.
Specifications:
Description
Polyclonal Antibody of 200 µl targeting IGF2BP3/IMP3 for IP, RIP, WB.
| Target: | IGF2BP3/IMP3 |
|---|---|
| Product Type: | Antibody |
| Size: | 200 μl |
| Application: | IP, RIP, WB |
| Research Area / Disease: | Epigenetics |
| Conjugate: | Unlabeled |
| Antibody Type: | Polyclonal |
| Concentration: | 1 mg/mL |
| Formulation: | 200 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained. |
| Immunogen: | Peptide bond synthesis HQQQKALQSGPPQSRRK KLH (563-579 aa) |
| Host Species: | Rabbit |
| Species Reactivity: | Human, Mouse |
| Source: | This antibody was purified from rabbit serum by affinity column chromatography. The rabbit was immunized with KLH conjugated synthetic peptide, HQQQKALQSGPPQSRRK corresponding to 563-579 aa. |
| Reactivity: | This antibody reacts with human IGF2BP3 (~64 kDa) on Western blotting, Immunoprecipitation and RNP Immunoprecipitation. |
| Gene ID Human: | |
| Gene ID Mouse: | |
| Storage Temperature: | -20°C |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
Citations
- Conway AE et al. Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival. Cell Rep. 15, 666-79 (2016),
- Degrauwe N et al. The RNA Binding Protein IMP2 Preserves Glioblastoma Stem Cells by Preventing let-7 Target Gene Silencing. Cell Rep 15, 1634-47 (2016),
- Lederer M et al. The role of the oncofetal IGF2 mRNA-binding protein 3 (IGF2BP3) in cancer. Semin Cancer Biol. 29, 3-12 (2014),
- Pasiliao CC et al. The involvement of insulin-like growth factor 2 binding protein 3 (IMP3) in pancreatic cancer cell migration, invasion, and adhesion. BMC Cancer 15, 266 (2015),
- Ueki A et al. Up-regulation of Imp3 confers in vivo tumorigenicity on murine osteosarcoma cells. PLoS One. 7, e50621 (2012)
- The RNA Binding Protein IMP2 Preserves Glioblastoma Stem Cells by Preventing let-7 Target Gene Silencing.
Derauwe N et al. Cell Rep. (2016) - Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival.
Conway AE et al. Cell Rep. 15, 666-79 (2016) - RNA-binding protein IGF2BP3 targeting of oncogenic transcripts promotes hematopoietic progenitor proliferation.
Palanichamy JK et al.
References
- Liao, B., et al., J. Biol. Chem. 280, 18517-18524 (2005)
- Monk, D., et al., J. Med. Genet. 39, 575-581 (2002)
- Nielsen, J., et al., Mol. Cell Biol. 19, 1262-1270 (1999)
- Mueller-Pillasch, F., et al., Oncogene 14, 2729-2733 (1997)
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