Anti-IGF2BP1 (IMP1) (Human) pAb (Polyclonal Antibody)

IGF2BP1/IMP1 Polyclonal Antibody.

Specifications:

Description

Polyclonal Antibody of 200 µl targeting IGF2BP1/IMP1 for IP, RIP, WB.

Target: IGF2BP1/IMP1
Product Type: Antibody
Size: 200 μl
Application: IP, RIP, WB
Research Area / Disease: Epigenetics
Conjugate: Unlabeled
Antibody Type: Polyclonal
Concentration: 1 mg/mL
Formulation: 200 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Immunogen: Peptide bond synthesis KQQHQKGQSNQAQARRK KLH (561-577 aa)
Host Species: Rabbit
Species Reactivity: Human, Mouse
Source: This antibody was purified from rabbit serum by affinity column chromatography. The rabbit was immunized with KLH conjugated synthetic peptide, KQQHQKGQSNQAQARRK corresponding to 561-577 aa.
Reactivity: This antibody reacts with human IGF2BP1 (~63 kDa) on Western blotting, Immunoprecipitation and RNP Immunoprecipitation.
Gene ID Human:

10642

Gene ID Mouse:

140486

Storage Temperature: '-20°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Citations

  1. Conway AE et al. Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival. Cell Rep. 15, 666-79,
  2. King DT et al. Assessing Specific Oligonucleotides and Small Molecule Antibiotics for the Ability to Inhibit the CRD-BP-CD44 RNA Interaction. PLoS One 9, e91585 (2014),
  3. Patel VL et al. Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control. Genes Dev. 26, 43-53 (2012),
  4. Stoskus M et al. ETV6/RUNX1 transcript is a target of RNA-binding protein IGF2BP1 in t(12;21)(p13;q22)-positive acute lymphoblastic leukemia. Blood Cells Mol Dis. 57, 30-4 (2016)
  5. Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival.
    Conway AE et al. Cell Rep. 15, 666-79 (2016) 

References

  1. Liao, B., et al., J. Biol. Chem. 280, 18517-18524 (2005)
  2. Ioannidis, P., et al., Int. J. Cancer 104, 54-59 (2003)
  3. Nielsen, J., et al., Mol. Cell. Biol. 19, 1262-1270 (1999)