Autophagy is a cellular self-digestion process for the purpose of providing nutrients to allow for cell survival during stress conditions. Autophagy can be selective (mitophagy) or non-selective (nutrient poor). Autophagy plays an important role in maintaining the cell homeostasis by removing non-essential cell components.
Recent research has also shown an association of mammalian autophagy with pathological conditions including neurodegenerative diseases, infection, cardiac disease, cancer and aging. Find our autophagy reagents for important targets such as LC3, p62/SQSTM1, ATG12, ATG, 14, ATG16L, ATG9, ULK1, and more.