Products Product Type Antibodies Polyclonal Anti-Atg5 pAb (Polyclonal Antibody)

Anti-Atg5 pAb (Polyclonal Antibody)

Atg5 Polyclonal Antibody.

Specifications:

Description

Polyclonal Antibody of 100 µl targeting Atg5 for WB.

Target:	Atg5
Product Type:	Antibody
Size:	100 µl
Application:	WB
Research Area / Disease:	Autophagy
Conjugate:	Unlabeled
Antibody Type:	Polyclonal
Formulation:	100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Isotype:	Affinity Purified Ig
Immunogen:	C-terminal peptide of human Atg5
Host Species:	Rabbit
Species Reactivity:	Human, Mouse, Rat
Source:	This antibody was purified from rabbit serum using affinity column. The rabbit was immunized with the synthetic peptide corresponding to C-terminus of human Atg5.
Reactivity:	This antibody reacts with Atg5-Atg12 complex (55 kDa) on Western blotting.
Gene ID Human:	9474
Gene ID Mouse:	11793
Storage Temperature:	-20°C
Regulatory Statement:	For Research Use Only. Not for use in diagnostic procedures.

Citations

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Myeku N, Figueiredo-Pereira ME. Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62. J Biol Chem. 286, 22426-40 (2011),
Ni HM et al. Dissecting the dynamic turnover of GFP-LC3 in the autolysosome. Autophagy 7, 188-204 (2011),
Ni HM et al. Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity. Am J Pathol. 183, 1815-25 (2013)
Li Y et al. Impaired Fasting-Induced Adaptive Lipid Droplet Biogenesis in Liver-Specific Atg5-Deficient Mouse Liver Is Mediated by Persistent Nuclear Factor-Like 2 Activation. Am J Pathol. 188, 1833-1846 (2018)
Shen J et al. Role of Autophagy in Zinc Oxide Nanoparticles-Induced Apoptosis of Mouse LEYDIG Cells. Int J Mol Sci. 20, pii: E4042 (2019)
Saladini S et al. Metformin Impairs Glutamine Metabolism and Autophagy in Tumour Cells. Cells 8, E49 (2019)
Wang, Jinglei, et al. “Tri-ortho-cresyl phosphate induces autophagy of mouse ovarian granulosa cells.” Reproduction 158.1 (2019): 61-69.
Yang, Si, et al. “Tea polyphenols alleviate tri‐ortho‐cresyl phosphate‐induced autophagy of mouse ovarian granulosa cells.” Environmental toxicology 35.4 (2020): 478-486.
Yang, Si, et al. “Tea polyphenols alleviate tri‐ortho‐cresyl phosphate‐induced autophagy of mouse ovarian granulosa cells.” Environmental toxicology 35.4 (2020): 478-486.
Cocco, Stefania, et al. “Inhibition of autophagy by chloroquine prevents resistance to PI3K/AKT inhibitors and potentiates their antitumor effect in combination with paclitaxel in triple negative breast cancer models.” Journal of Translational Medicine 20.1 (2022): 290.
Yang, Si, et al. “Role of autophagy in lysophosphatidylcholine-induced apoptosis of mouse ovarian granulosa cells.” International journal of molecular sciences 23.3 (2022): 1479.