Anti-PIWIL2 (MILI) (Mouse) pAb (Polyclonal Antibody)

PIWIL2 Polyclonal Antibody.

Specifications:

Description

Polyclonal Antibody of 100 µl targeting PIWIL2 for IP, WB.

Target: PIWIL2
Product Type: Antibody
Size: 100 µl
Application: IP, WB
Research Area / Disease: Autophagy
Conjugate: Unlabeled
Antibody Type: Polyclonal
Formulation: 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Isotype: Affinity Purified Ig
Immunogen: Synthetic peptide corresponding to PIWIL2 VRKDREEPRSSLPDPS mouse (107-122 aa)
Host Species: Rabbit
Species Reactivity: Mouse
Source: This antibody was purified from rabbit serum using affinity column. The rabbit was immunized with the synthetic peptide, VRKDREEPRSSLPDPS, corresponding to mouse PIWIL2 (107-122 aa).
Reactivity: This antibody reacts with MILI onWestern blotting and Immunoprecipitation.
Gene ID Human:

55124

Gene ID Mouse:

57746

Storage Temperature: -20°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Citations

  1. Kojima K et al. Associations between PIWI proteins and TDRD1/MTR-1 are critical for integrated subcellular localization in murine male germ cells. Genes Cells. 14, 1155-65 (2009),
  2. Kuramochi-Miyagawa S et al. MVH in piRNA processing and gene silencing of retrotransposons. Genes Dev. 24, 887-92 (2010),
  3. Kuramochi-Miyagawa S et al. DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev. 22, 908-17 (2008),
  4. Shiromoto Y et al. GPAT2, a mitochondrial outer membrane protein, in piRNA biogenesis in germline stem cells. RNA 19, 803-10 (2013)
  5. Kuramochi-Miyagawa, S., et al., Genes & Dev. 22, 908-917 (2008)
  6. Ding D et al. Mitochondrial membrane-based initial separation of MIWI and MILI functions during pachytene piRNA biogenesis. Nucleic Acids Res. 47, 2594-2608 (2019)rn

References

  1. Aravin, A. A., et al., Science 316, 744-747 (2007)
  2. Aravin, A., et al., Nature 442, 203-207 (2006)
  3. Kuramochi-Miyagawa, S., et al., Development 131, 839-849 (2004)
  4. Kuramochi-Miyagawa, S., et al., Mech. Dev. 108, 121-133 (2001)