Anti-Atg14 (Human) pAb

  • Applications
    • IP
    • WB
  • Target Atg14
  • Host Species Rabbit
  • Species Reactivities Human, Mouse, Rat
  • Code # PD026
  • Size 100 µl
  • Price
    $457.61
Specifications

Alternative Names

ATG14, autophagy related 14, ATG14L, BARKOR KIAA0831, Atg14L, 4832427M01, D14Ertd114e,D14Ertd436e

Background

Autophagy is a process of intracellular bulk degradation in which cytoplasmic components including organelles are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. Mammalian homologues of Atg14/Atg14L/BARKOR localizes on the isolation membrane and autophagosome, and it necessary for autophagosome formation. Atg14 binds to the PI3K complex (Beclin-1, Vps34, Vps15) and promotes the autophagosome formation.
  • Antibody Type:
    Polyclonal
  • Application:
    IP, WB
  • Conjugate:
    Unlabeled
  • Description:

    Polyclonal Antibody of 100 µl targeting Atg14 for IP, WB.

  • Formulation:
    100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
  • Gene ID (Human):
  • Gene ID (Mouse):
  • Gene ID (Rat):
  • Host Species:
    Rabbit
  • Immunogen:
    Recombinant human Atg14 (167-404 a.a.)
  • Isotype:
    Affinity Purified Ig
  • Product Type:
    Antibody
  • Reactivity:
    This antibody reacts with human, mouse and rat Atg14 on Western blotting and Immunoprecipitation.
  • Research Area:
    Autophagy
  • Short Description:

    Atg14 Polyclonal Antibody.

  • Size:
    100 µl
  • Species Reactivity:
    Human, Mouse, Rat
  • Storage Temperature:
    -20°C
  • Target:
    Atg14
Citations
  1. Maejima Y et al. Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. Nat Med. 19, 1478-88 (2013),
  2. Hamasaki M et al. Autophagosomes form at ER-mitochondria contact sites. Nature. 495, 389-93 (2013)
  3. Itakura, E., et al., Mol. Biol. Cell 19, 5360-5372 (2008)
References
  1. Matsunaga, K., et al., Nat. Cell Biol. 11, 385-396 (2009)
  2. Zhong, Y., et al., Nat. Cell Biol. 11, 468-476 (2009)
  3. Sun, Q., et al., PNAS 105, 19211-19216 (2008)