Anti-Beclin 1 (Human) pAb (Polyclonal Antibody)
Specifications:
Description
| Target: | Beclin 1 |
|---|---|
| Product Type: | Antibody |
| Size: | 100 μg |
| Application: | ICC, IP, WB |
| Research Area / Disease: | Autophagy |
| Conjugate: | Unlabeled |
| Antibody Type: | Polyclonal |
| Formulation: | In PBS/50% glycerol, pH 7.2 |
| Isotype: | Affinity Purified Ig |
| Immunogen: | Full-length recombinant human Beclin 1 |
| Host Species: | Rabbit |
| Species Reactivity: | Hamster, Human, Mouse, Rat |
| Reactivity: | This antibody reacts with Beclin 1 on Western blotting, Immunoprecipitation and Immunocytochemistry. |
| Storage Temperature: | -20°C |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
Citations
- Berliocchi L et al. Autophagy impairment in a mouse model of neuropathic pain. Mol Pain. 7, 83 (2011),
- Hamasaki M et al. Autophagosomes form at ER-mitochondria contact sites. Nature 495, 389-93 (2013),
- Matsunaga K et al. Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L. J Cell Biol. 190, 511-21 (2010),
- Russo R et al. Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivo. Cell Death Dis. 2, e144 (2011)
- Lin X et al. Liver-specific deletion of Eva1a/Tmem166 aggravates acute liver injury by impairing autophagy. Cell Death Dis. 9, 768 (2018)
- Zhang Yet al. TGF-β3 Promotes MUC5AC Hyper-Expression by Modulating Autophagy Pathway in Airway EBioMedicine. 33, 242-252 (2018)
- Hagio-Izaki K et al. Lipopolysaccharide induces bacterial autophagy in epithelial keratinocytes of the gingival sulcus. BMC Cell Biol. 19, 18 (2018)
- Jin GL et al. Koumine Decreases Astrocyte-Mediated Neuroinflammation and Enhances Autophagy, Contributing to Neuropathic Pain From Chronic Constriction Injury in Rats. Front Pharmacol. 9, 989 (2018)
- Sase K et al. Involvement of Beclin‑1 in axonal protection by short‑term hyperglycemia against TNF‑induced optic nerve damage. Mol Med Rep. 18, 5455-5460 (2018)
- Wang M et al. WDR81 regulates adult hippocampal neurogenesis through endosomal SARA-TGFβ signaling. Mol Psychiatry (2018) In press
- Nakajima S et al. Fat-specific protein 27α inhibits autophagy-dependent lipid droplet breakdown in white adipocytes. J Diabetes Investig. in press.
- Shen J et al. Role of Autophagy in Zinc Oxide Nanoparticles-Induced Apoptosis of Mouse LEYDIG Cells. Int J Mol Sci. 20, pii: E4042 (2019)
- Chen, YJ., Knupp, J., Arunagiri, A. et al. PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones. Nat Commun 12, 5991 (2021).
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