The MBL Bion MUMPS-G ANTIBODY TEST SYSTEM utilizes the indirect fluorescent antibody assay to be used with human serum.
The MBL Bion MUMPS-G ANTIBODY TEST SYSTEM is an indirect fluorescent antibody assay for the qualitative and/or semi-quantitative determination of Mumps IgG antibodies in human serum. The MBL Bion MUMPS-G ANTIBODY TEST SYSTEM is intended for use as an aid in the diagnosis of primary infection and as a determination of immune status.
The incubation period for Mumps Virus ranges between 18 and 21 days. Infections are spread by droplets via the upper respiratory route. Between 25 and 50 percent of all infections are silent. Immunity after infection appears to be lifelong; however, silent reinfections may occur although it is probably an infrequent event. An attenuated live virus vaccine is available which induces lower levels of measurable antibody than natural infection. Only one distinct antigenic type of Mumps Virus is known. Some antigenic cross-reactivity and anamnestic antibody responses exist with other Paramyxoviruses, particularly Parainfluenza Type 1, in some serological tests. However, cross-reacting antibodies do not appear to be a problem when testing for Mumps Virus antibody by immunofluorescence. Paired serum samples should be used for serological analysis, and the initial specimen should be obtained as early as possible after the onset of symptoms. IgG antibodies appear within the first week, reach high titers, and persist as protective antibody for apparent lifelong immunity.