Mumps Virus IgG Test Kit

  • Applications
    • IF
  • Code # MUG-120
  • Size 120 tests
  • Price Call for Price
Specifications

Background

The incubation period for Mumps Virus ranges between 18 and 21 days. Infections are spread by droplets via the upper respiratory route. Between 25 and 50 percent of all infections are silent. Immunity after infection appears to be lifelong; however, silent reinfections may occur although it is probably an infrequent event. An attenuated live virus vaccine is available which induces lower levels of measurable antibody than natural infection. Only one distinct antigenic type of Mumps Virus is known. Some antigenic cross-reactivity and anamnestic antibody responses exist with other Paramyxoviruses, particularly Parainfluenza Type 1, in some serological tests. However, cross-reacting antibodies do not appear to be a problem when testing for Mumps Virus antibody by immunofluorescence. Paired serum samples should be used for serological analysis, and the initial specimen should be obtained as early as possible after the onset of symptoms. IgG antibodies appear within the first week, reach high titers, and persist as protective antibody for apparent lifelong immunity.

  • Application:
    IF
  • Components:
    • Mumps Substrate Slide, ten slides, twelve wells each (Code# MU-8012)
    • Conjugate, IgG with Counterstain, 2 x 3.5 mL (Code# CCG-9972)
    • Mumps IgG Positive Control Serum, 0.5 mL (Code# MUG-8020)
    • Mumps Negative Control Serum, 0.5 mL (Code# MUN-8010)
    • PBS Packet, 2 x 1 Liter (Code# PBS-9990)
    • Mounting Medium, 3.5 mL (Code# MM-9985)
  • Description:

    The MBL Bion MUMPS-G ANTIBODY TEST SYSTEM utilizes the indirect fluorescent antibody assay to be used with human serum.

    INTENDED USE

    The MBL Bion MUMPS-G ANTIBODY TEST SYSTEM is an indirect fluorescent antibody assay for the qualitative and/or semi-quantitative determination of Mumps IgG antibodies in human serum. The MBL Bion MUMPS-G ANTIBODY TEST SYSTEM is intended for use as an aid in the diagnosis of primary infection and as a determination of immune status.

  • Product Type:
    Kit
  • Research Area:
    Infectious Disease
  • Size:
    120 tests
References
  1. Norrby, E., Mumps Virus, in Manual of Clinical Microbiology, 4th Ed., Lennette, E.H., A. Balows, W.J. Hausler, Jr., H.J. Shadomy., (eds), American Society for Microbiology,
    Washington, D.C., 774-778, 1985.
  2. Kleiman, M.B., Mumps Virus Infections, in Laboratory Diagnosis of Viral Infections, Lennette,E.H. (Ed.), Marcel Dekker, Inc., New York, 369-383, 1985.
  3. Hopps, H.E., and P.D. Parkman, Mumps Virus, in Diagnostic Procedures for Viral, Rickettsial and Chlamydial Infections, 5th Ed., Lennette, E.H. and N.H. Schmidt (eds), American Public Health Association, Washington, D.C., 633-653, 1979.
  4. Rossier, E., H.R. Miller, P.H. Phipps, Mumps Virus Antibody, in Rapid Viral Diagnosis by Immunofluorescence, An Atlas and Practical Guide, Univ. of Ottawa Press, Ottawa, 139-140, 1989.
  5. Ukkonen, P., M.L. Granstrom, J. Rasanen, M.E. Salonen, and K. Penttinen, Mumps Specific Immunoglobulin M and G Antibodies in Natural Mumps Infection as Measured by Enzyme-linked Immunosorbent Assay, J. Med. Virol 8:131-142, 1981.
  6. Weller, T.H., A.H. Coons, Fluorescent Antibody Studies with Agents of Varicella and Herpes Zoster Propagated In Vitro, Proc. Soc. Exp. Biol. Med., 86:789-794, 1954.
  7. Riggs, J.L., R.J. Seiwald, J.H. Burckhalter, C.M. Downs, T.G. Metcalf, Isothiocyanate Compounds as Fluorescent LabelingAgents for Immune Serum, Am. J. Pathol., 34:1081-1097, 1958.
  8. Lyerla, H.C., F.T. Forrester, The Immunofluorescence (IF) Test, in Immunofluorescence Methods in Virology, USDHHS, Georgia, 71-81, 1979.
  9. Holborow, E.J., D.M. Weir, G.D. Johnson, A Serum Factor in Lupus Erythematosus With Affinity for Tissue Nuclei, Br. Med. J., 11:732-734, 1957.
  10. Berg, P.A., I. Roitt, D. Doniach, H.M. Cooper, Mitochondrial Antibodies in Primary Biliary Cirrhosis, Immunol., 17:281-293, 1969.
  11. Chernesky, M.A., C.G. Ray, T.F. Smith, Laboratory Diagnosis of Viral Infections, Cumitech 15, ASM, Washington, D.C., March 1982.
  12. Black, F.L., and L.L. Berman, Measles and Mumps, in Manual of Clinical Laboratory Immunology, 3rd Ed., Rose, N.R., H. Freidman, and J.H. Fahey, (eds), American Society for Microbiology, Washington, D.C., 532-535, 1986.
  13. Zaia, J.A., N.N. Oxman, Antibody to Varicella-Zoster Virus Induced Membrane Antigen: ImmunofluorescenceAssay Using Monodispersed Glutaraldehyde-Fixed Target Cells, J. Inf. Diseases, 136:519-530, 1977.
  14. Data on file, MBL Bion, Des Plaines, Illinois.
  15. Personal Communications, Smith, T., Director, Department of Clinical Microbiology, Virology Laboratory, Mayo Clinic.