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MHC Class I & II Tetramers

MHC Monomers

CD1d Tetramers

TCRs recognize and bind to complexes composed of MHC molecules and specific peptides expressed on the surface of antigen-presenting cells.  We have tetramerized and biotinylated with streptavidin to maintain stable binding to multiple TCR, enabling MHC/peptide tetramers to be used as detection tools.  Phycoerythrin (PE), allophycocyanin (APC), or Brilliant Violet™ 421 (BV421) fluorophores are available for detection of antigen-specific T cells by flow cytometry or fluorescence microscopy using our MHC Multimers.

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Learn about the types of MHC Molecules

 Superior Specificity with Patented α3 Mutation

Impact of α3 Mutation

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