Anti-Fas (CD95) (Human) mAb (Monoclonal Antibody)

Fas Monoclonal Antibody.

Specifications:

Description

Monoclonal Antibody of 100 μg targeting Fas for FCM, NT, WB.

Target: Fas
Product Type: Antibody
Size: 100 μg
Application: FCM, NT, WB
Research Area / Disease: Apoptosis
Conjugate: Unlabeled
Antibody Type: Monoclonal
Clone Number: ZB4
Concentration: 1 mg/mL
Formulation: 100 μg IgG in 100 μl volume of PBS containing 1% BSA and 0.09% NaN3.
Isotype: IgG1
Immunogen: Recombinant human Fas
Host Species: Mouse
Species Reactivity: Human
Source: This antibody was purified from hybridoma(clone ZB4) supernatant using protein A agarose. Thishybridoma was established by fusion of mouse myelomacell NS-1 with Balb/c mouse splenocyte immunized withrecombinant human Fas.
Reactivity: This antibody reacts with human Fas onWestern blotting and Flow cytomet ry. It does not react withmouse Fas.
Gene ID Human:

355

Gene ID Mouse:

14102

Storage Temperature: '-20°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Citations

  1. Chiou SH, et al., The immediate early 2 protein of human cytomegalovirus (HCMV) mediates the apoptotic control in HCMV retinitis through up-regulation of the cellular FLICE-inhibitory protein expression. J Immunol. 177:6199-206. 2006,
  2. Chiou SH, et al., Up-regulation of Fas ligand expression by human cytomegalovirus immediate-early gene product 2: a novel mechanism in cytomegalovirus-induced apoptosis in human retina. J Immunol. 167:4098-103. 2001,
  3. Zanin-Zhorov A, et al., Fibronectin-associated Fas ligand rapidly induces opposing and time-dependent effects on the activation and apoptosis of T cells. J Immunol. 171:5882-9. 2003
    1. Jing ZT et al. Hepatitis B Virus Surface Antigen Enhances the Sensitivity of Hepatocytes to Fas-Mediated Apoptosis via Suppression of AKT Phosphorylation. J Immunol. 201, 2303-2314 (2018)

    References

    1. Arokium, H., et al., J. Virol. 83, 11283-11297 (2009)
    2. Giammarioli, A. M., et al., Cancer Res. 68, 5291-5300 (2008)
    3. Schumann, D. M., et al., PNAS 104, 2861-2866 (2007)
    4. Maedler, K., et al., Diabetes 55, 2713-2722 (2006)
    5. Gilhar, A., et al., Am. J. Pathol. 168, 170-175 (2006)
    6. Ito, K., et al., Cancer Res. 65, 4417-4424 (2005)
    7. Ahmed, F., et al., Blood 103, 2079-2087 (2004)
    8. Holler, N., et al., Mol. Cell. Biol. 23, 1428- 1440 (2003)
    9. Maedler, K., et al., PNAS 99, 8236-8241 (2002)
    10. Maedler, K., et al., Diabetes 50, 1683-1690 (2001)
    11. Jiang, S., et al., Invest. Ophthalmol. Vis. Sci. 41, 645-655 (2000)
    12. Landowski, T. H., et al., Blood 94, 265-274 (1999)
    13. Agrawal, S., et al., J. Clin. Invest. 102, 1715-1723 (1998)
    14. Giordano, C. et al., Science 275, 960-963 (1997)
    15. Boirivant, M., et al., J. Clin. Invest. 98, 2616-2622 (1996)
    Code MD-11-3
    Product Type Antibody
    Size 100 μg
    Application FCM, NT, WB
    Price
    $328.61
    Qty:

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