Anti-Phospho-p62 (SQSTM1) (Ser351) mAb (Monoclonal Antibody)

Phospho-p62 (SQSTM1) (Ser351) Monoclonal Antibody.

Specifications:

Description

Monoclonal Antibody of 100 µl targeting Phospho-p62 (SQSTM1) (Ser351) for WB,ICC,IHC.

Target: Phospho-p62 (SQSTM1) (Ser351)
Product Type: Antibody
Size: 100 µl
Application: ICC, IHC, WB
Research Area / Disease: Autophagy
Conjugate: Unlabeled
Antibody Type: Monoclonal
Clone Number: 5D5
Formulation: 1 mg/mL in PBS/50% glycerol, pH 7.2
Isotype: IgG1 ĸ
Immunogen: KLH conjugated synthetic peptide, CKEVDP(pS)TGELQSLQ (corresponding to amino acid residues 346-359 of mouse p62 (SQSTM1))
Host Species: Mouse
Species Reactivity: Human, Mouse
Source: Purified IgG from hybridoma supernatant
Gene ID Human:

8878

Gene ID Mouse:

18412

Storage Temperature: -20°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Citations

  1. Yang, Song, et al. “Ginseng root extract attenuates inflammation by inhibiting the MAPK/NF-κB signaling pathway and activating autophagy and p62-Nrf2-Keap1 signaling in vitro and in vivo.” Journal of Ethnopharmacology 283 (2022): 114739.
  2. Yamashita S et al. CYLD dysregulation in pathogenesis of sporadic inclusion body myositis. Sci Rep. 9, 11606 (2019)
  3. Wang Z et al. The expression of p-p62 and nuclear Nrf2 in esophageal squamous cell carcinoma and association with radioresistance. Thorac Cancer. 11, 130-139 (2019)

References

  1. Kageyama, S., et al., J. Biol. Chem. 289, 24944-24955 (2014)
  2. Ichimura, Y., et al., Mol. Cell 51, 618-631 (2013)