Anti-UVRAG (Human) mAb

  • Applications
    • WB
  • Target UVRAG
  • Host Species Mouse
  • Species Reactivities Hamster, Human, Mouse, Rat
  • Code # M160-3
  • Size 100 μg
  • Price
    $243.29
Specifications

Alternative Names

UV radiation resistance associated, p63, DHTX, VPS38

Background

Autophagy is a process of intracellular bulk degradation in which cytoplasmic components including organelles are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. Autophagy has two ubiquitin-like conjugation systems, the Atg12 and LC3-II systems. In the Atg12 conjugation system, the Atg12-Atg5-Atg16L forms 800 kDa complex that elongates autophagic isolation membrane. After completion of the formation of the autophagosome, the Atg12-Atg5-Atg16L complex dissociates from the membrane.
  • Antibody Type:
    Monoclonal
  • Application:
    WB
  • Clone Number:
    1H4
  • Concentration:
    1 mg/mL
  • Conjugate:
    Unlabeled
  • Description:
  • Formulation:
    100 μg IgG in 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
  • Host Species:
    Mouse
  • Immunogen:
    Recombinant human UVRAG (389-699 a.a.)
  • Isotype:
    IgG2a ĸ
  • Product Type:
    Antibody
  • Reactivity:
    This antibody reacts with UVRAG onWestern blotting.
  • Research Area:
    Apoptosis
  • Short Description:
  • Size:
    100 μg
  • Species Reactivity:
    Hamster, Human, Mouse, Rat
  • Storage Temperature:
    -20°C
  • Target:
    UVRAG
Citations
  1. Huang W et al., Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein. Cell Res. 22, 473-489 (2012)