Anti-Neuropsin (Mouse) mAb (Monoclonal Antibody)
Neuropsin Monoclonal Antibody.
Specifications:
Description
Monoclonal Antibody of 100 μg targeting Neuropsin for ICC, IHC, IPP, NT, WB.
| Target: | Neuropsin |
|---|---|
| Product Type: | Antibody |
| Size: | 100 μg |
| Application: | ICC, IHC, IP, NT, WB |
| Research Area / Disease: | Immunology |
| Conjugate: | Unlabeled |
| Antibody Type: | Monoclonal |
| Clone Number: | MabB5 |
| Formulation: | This antibody is lyophilized form. Prepare a stock solution by dissolving the lyophilized antibody with 100 mL of distilled water. After reconstitution, IgG concentration should be 1 mg/mL in PBS (pH 7.2)/1% Sucrose. No preservative is contained. |
| Isotype: | IgG2a |
| Immunogen: | Recombinant protein |
| Host Species: | Rat |
| Species Reactivity: | Mouse |
| Source: | This antibody was purified from rat ascitesfluid using protein A agarose. This hybridoma (cloneMabB5) was established by fusion of rat myeloma cellY3Ag1.2.3 with Wister rat splenocyte immunized with therecombinant protein. |
| Reactivity: | This antibody reacts with mouseneuropsin (32 kDa) on Western blotting with total celllysate from neuropsin overexpressed insect cell. |
| Gene ID Human: | |
| Gene ID Mouse: | |
| Storage Temperature: | -20°C |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
Citations
- Inoue N et al. Expression of neuropsin in the keratinizing epithelial tissue-immunohistochemical analysis of wild-type and nude mice. J Invest Dermatol. 110, 923-31 (1998),
- Kato K et al. Serine proteinase inhibitor 3 and murinoglobulin I are potent inhibitors of neuropsin in adult mouse brain. J Biol Chem. 276, 14562-71 (2001),
- Matsumoto-Miyai K et al. NMDA-dependent proteolysis of presynaptic adhesion molecule L1 in the hippocampus by neuropsin. J Neurosci. 23, 7727-36 (2003),
- Momota Y et al. Blockade of neuropsin, a serine protease, ameliorates kindling epilepsy. Eur J Neurosci. 10, 760-4 (1998),
- Oka T et al. Role of loop structures of neuropsin in the activity of serine protease and regulated secretion. J Biol Chem. 277, 14724-30 (2002),
- Shimizu C et al. Characterization of recombinant and brain neuropsin, a plasticity-related serine protease. J Biol Chem. 273, 11189-96 (1998),
- Tamura H et al. Neuropsin is essential for early processes of memory acquisition and Schaffer collateral long-term potentiation in adult mouse hippocampus in vivo. J Physiol. 570, 541-51 (2006)
References
- Tamura, H., et al., J. Physiol. 570, 541-551 (2006)
- Matsumoto-Miyai, K., et al., J. Neurosci. 23, 7727-7736 (2003)
- Oka, T., et al., J. Biol. Chem. 277, 14724-14730 (2002)
- Kato, K., et al., J. Biol. Chem. 276, 14562-14571 (2001)
- Momota, Y., et al., Eur. J. Neurosci. 10, 760-764 (1998)
- Shimizu, C., et al., J. Biol. Chem. 273, 11189-11196 (1998)
- Inoue, N., et al., J. Invest. Dermatol. 110, 923-931 (1998)
- Chen, Z. L., et al., J. Histochem. Cytochem. 46, 313-320 (1998)
- Okabe, A., et al., Brain Res. 728, 116-120 (1996)
- Chen, Z. L., et al., J. Neurosci. 15, 5088-5097 (1995)
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Pathway Posters
Rho Family Pathway
