Tim-3 Polyclonal Antibody

  • Applications
    • WB
  • Target Tim-3
  • Species Reactivities Human
  • Code # JM-3808-100
  • Size 100 µg
  • Price
    $321.65
Specifications

Alternative Names

tim-3, tim3, tim 3, TIMD3, TIMD-3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell membrane protein 3

Background

As a member of the T cell immunoglobulin and mucin domain (TIM) family, Tim-3 is reported to promote or terminate Th1 immunity and is thought to influence a range of inflammatory conditions. It is constitutively expressed in a subset of murine IFNgamma-secreting Th1 cells, but not Th2 cells, in both human and mice. Additionally, Tim-3 is expressed dendritic cells, and by a subset of CD4+ cells where its levels of expression increase upon anti-CD3/28 stimulation. This molecule is also highly expressed in in vitro polarized Th1 cells, and at lower levels in Th17 cells. It is known to synergize with Toll-like receptors and is thought to regulate Th1 and Th17 cytokine secretion.
  • Antibody Type:
    Polyclonal
  • Application:
    WB
  • Concentration:
    0.5 mg/ml
  • Conjugate:
    Unlabeled
  • Description:
    Tim-3 Primary Antibody of 100 µg.
  • Product Type:
    Antibody
  • Research Area:
    Immunology
  • Short Description:
    Tim-3 Primary Antibody.
  • Size:
    100 µg
  • Species Reactivity:
    Human
  • Storage Temperature:
    -20°C
  • Target:
    Tim-3