Active Human Caspase-8

  • Target Caspase-8
  • Code # JM-1088-25
  • Size 25 Units
  • Price
    $255.64
Specifications

Alternative Names

Active Human Caspase-8, Active Caspase-8, Caspase-8 Enzyme, Recombinant caspase-8, human caspase-8, human caspases, active caspases

Background

Caspase-8 (also know as FLICE, MASH, Mch5) is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-8 also exists in cells as an inactive proenzyme. During apoptosis procaspase-8 is processed at aspartate residues by self-proteolysis and/or cleavage by another caspase. The processed active form of caspase-8 consists of large and small subunits which associate to form the active enzyme. Active caspase-8 has been shown to activate caspase-3 leading to degradation of a variety of cellular target proteins during apoptosis. The recombinant active human caspase-8 was expressed in E. coli.
  • Description:
    Caspase-8 Protein of 25 Units.
  • Product Type:
    Recombinant Protein
  • Purity:
    ≥95% by SDS Page
  • Research Area:
    Apoptosis
  • Short Description:
    Caspase-8 Protein.
  • Size:
    25 Units
  • Storage Temperature:
    -70°C
  • Target:
    Caspase-8