Active Human Caspase-1

  • Target Caspase-1
  • Code # JM-1081-25
  • Size 25 Units
  • Price
    $255.77
Specifications

Alternative Names

Active Human Caspase-1, Active Caspase-1, Caspase-1 Enzyme, Recombinant caspase-1, human caspase-1, human caspases, active caspases

Background

Caspase-1 (also know as ICE) is a prototypical member of the caspase-family of cysteine proteases. Caspase-1 exists in cells as an inactive 45 kDa proenzyme. The pro-enzyme is matured by proteolysis to yield large (20 kD) and small (10 kD) subunits. The active caspase-1 is a heterotetramer consisting of two large and two small subunits. To date the regulatory mechanism of caspase-1 activation and the role of caspase-1 in apoptosis are poorly understood. In THP-1 cells, a large proportion of the caspase-1 is present in the inactive proenzyme form. The recombinant active human caspase-1 was expressed in E. coli.
  • Description:
    Caspase-1 Protein of 25 Units.
  • Product Type:
    Recombinant Protein
  • Research Area:
    Apoptosis
  • Short Description:
    Caspase-1 Protein.
  • Size:
    25 Units
  • Storage Temperature:
    -70°C
  • Target:
    Caspase-1