Magnosphere™ MS160/Tosyl

DATA SHEET

Magnosphere™ MS160/Tosyl beads are magnetic microparticles designed for covalent immobilization of ligands containing -NH2 groups for bioseparation. Their surfaces are covered with a JSR Life Sciences proprietary hydrophilic polymer, on which Tosyl group is incorporated as an active group. The Tosyl group makes it possible to immobilize ligands such as antibody without using coupling reagents. As the hydrophobic Tosyl group is eliminated though a coupling reaction, surface of the beads became hydrophilic after the reaction. This chemistry enables ligands to keep their function high and achieve a high yield and low non-specific binding bioseparation. Uniform particle size and superparamagnetic property of the Magnosphere™ MS160/Tosyl beads help good magnetic separation and re-suspension response. These characters of the beads are ideal for variety of applications such as enzyme immunoassay, immnoprecipitation-western blot.

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