The MBL Bion EPSTEIN-BARR EARLY ANTIGEN (DIFFUSE) ANTIGEN SUBSTRATE SLIDES may be utilized in the indirect fluorescent antibody assay method. Each lot is tested with a panel of titered sera to ensure sensitivity lot to lot; both positive and negative cells are in each well to provide a built-in control.
For Research Use Only
The Epstein-Barr Virus (EBV) was first detected and described by Epstein, Barr and Achong in electron-microscopic studies of lymphoblastoid cultures obtained from patients with Burkitt’s Lymphoma.The etiologic role of EBV in Infectious Mononucleosis (IM) was first reported in 1968 and has since been well documented to be the causative agent. Infection with EBV results in the expression of several viral proteins to which the host responds with appropriate antibodies.
MBL Bion EPSTEIN-BARR EARLY ANTIGEN (DIFFUSE) SUBSTRATE SLIDES are individually foil-wrapped twelve well slides with a mixture of lymphocytic cells (Raji) that have been infected with Epstein-Barr Virus (P3HR-1 strain) fixed onto each well. Each well contains an average of 10-20% infected cells per 200X field.