Anti-CD61 (GPIIIa) (Human) mAb-Biotin

  • Applications
    • FCM
  • Target CD61
  • Host Species Mouse
  • Species Reactivities Human
  • Code # D281-6
  • Size 50 µL
  • Price
    $233.93
Specifications

Alternative Names

ITGB3, integrin subunit beta 3, GP3A

Background

Glycoprotein IIIa, a β3 (CD61) subunit of integrin αIIbβ3 (CD41/CD61), acts as a fibrinogen receptor on the platelet surface. A mouse monoclonal antibody, T74, recognizes human β3 (CD61) subunit and inhibits platelet aggregation induced by several agonists such as collagen, ADP, and thrombin. T74 inhibits clot-retraction mediated by platelets or αvβ3-expressing cells when induced by thrombin. Western-blot analysis is not possible. T74 fails to bind to platelets from patients with Glanzmann’s thrombasthenia.
  • Antibody Type:
    Monoclonal
  • Application:
    FCM
  • Clone Number:
    T74
  • Conjugate:
    Biotin
  • Formulation:
    1 mg/mL in PBS/1% BSA/0.1% ProClin 150
  • Host Species:
    Mouse
  • Immunogen:
    Human thrombocyte
  • Product Type:
    Antibody
  • Research Area:
    Immunology
  • Size:
    50 µL
  • Species Reactivity:
    Human
  • Storage Temperature:
    4°C
  • Target:
    CD61