Anti-CD8 (Mouse) mAb-Alexa Fluor® 647

  • Applications
    • FCM
  • Target CD8
  • Host Species Rat
  • Species Reactivities Mouse
  • Code # D271-A64
  • Size 50 μl
  • Price
    $306.33
Specifications

Background

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two  chains, or a heterodimer composed of one  and one  chain. Both  and  chains share significant homology to immunoglobulin variable light chains. CD8  chains binds to class-I MHC molecules 3 domains. CD8 identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. This monoclonal antibody KT15 reacts with a non-polymorphic epitope on the mouse CD8  chain (mouse Ly2.1 and Ly2.2 cells).
  • Antibody Type:
    Monoclonal
  • Application:
    FCM
  • Clone Number:
    KT15
  • Concentration:
    1 mg/mL
  • Conjugate:
    Alexa Fluor® 647
  • Description:
    Monoclonal antibody of 50 µl targeting CD8 for FCM.
  • Formulation:
    50 μg IgG in 50 μl volume of PBS containing 1% BSA and 0.09% NaN3.*Azide may react with copper or lead in plumbing system to formexplosive metal azides. Therefore, always flush plenty of waterwhen disposing materials containing azide into drain.
  • Gene ID (Human):
  • Gene ID (Mouse):
  • Host Species:
    Rat
  • Immunogen:
    C6 antigen-specific CTL clone H-Y
  • Isotype:
    IgG2a λ
  • Product Type:
    Antibody
  • Reactivity:
    This antibody reacts with mouse CD8 α antigen on Flow cytometry.
  • Research Area:
    Immunology
  • Short Description:
    CD8 Monoclonal Antibody.
  • Size:
    50 μl
  • Species Reactivity:
    Mouse
  • Storage Temperature:
    4°C
  • Target:
    CD8
References
  1. Whiteland, J. L., et al., J. Histochem. Cytochem. 43, 313-320 (1995)
  2. Tomonari, K., and Lovering, E., Immunogenetics 28, 445-451 (1988)