Anti-MFG-E8 (Mouse) mAb (Monoclonal Antibody)

MFG-E8 Monoclonal Antibody.

Specifications:

Description

Monoclonal antibody of 100 μg targeting MFG-E8 for IHC, WB.

Target: MFG-E8
Product Type: Antibody
Size: 100 μg
Application: IHC, WB
Research Area / Disease: Apoptosis
Conjugate: Unlabeled
Antibody Type: Monoclonal
Clone Number: 18A2-G10
Concentration: 1 mg/mL
Formulation: 100 μg IgG in 100 μl volume of PBS containing 50% glycerol, pH 7.2. Contains nopreservatives.
Isotype: IgG
Immunogen: Recombinant mouse MFG-E8
Host Species: Hamster
Species Reactivity: Mouse
Source: This antibody was purified from hybridoma (clone 18A2-G10) supernatant using protein A agarose. This hybridoma was established by fusion of mouse myeloma cell with Armenian hamster lymph node immunized with the recombinant mouse MFG-E8.
Reactivity: This antibody reacts with mouse MFG-E8 short and long forms on Western blotting and Immunohistochemistry.
Gene ID Human:

4240

Gene ID Mouse:

17304

Storage Temperature: '-20°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Citations

  1. Abe T et al. Regulation of osteoclast homeostasis and inflammatory bone loss by MFG-E8. J Immunol. 193, 1383-91 (2014),
  2. Aziz M et al. Milk fat globule-epidermal growth factor-factor 8 attenuates neutrophil infiltration in acute lung injury via modulation of CXCR2. J immunol. 189, 393-402 (2012),
  3. Aziz MM et al. Prolactin induces MFG-E8 production in macrophages via transcription factor C/EBPbeta-dependent pathway. Apoptosis. 13, 609-20 (2008),
  4. Bobrie A et al. Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation. J Extracell Vesicles. 1, 18397 (2012),
  5. Hoffhines AJ et al. Tyrosylprotein sulfotransferase-2 expression is required for sulfation of RNase 9 and Mfge8 in vivo. J Biol Chem. 284, 3096-105 (2009),
  6. Jinushi M et al. MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF. J Clin Invest. 117, 1902-13 (2007),
  7. Kranich J et al. Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8. J Exp Med. 205, 1293-302 (2008),
  8. Middendorp S et al. Mice deficient for CD137 ligand are predisposed to develop germinal center-derived B-cell lymphoma. Blood. 114, 2280-9 (2009),
  9. Yoshino M et al. Analysis of capturing skin antigens in the steady state using milk fat globule EGF factor 8-deficient skin-hyperpigmented mice. Immunol Lett. 115, 131-37 (2008)

References

  1. Middendorp, S., et al., Blood. 114, 2280-9 (2009) [IHC]
  2. Kranich, J., et al., J. Exp. Med. 205, 1293-1302 (2008) [IHC]
  3. Aziz, M. M. et al., Apoptosis. 13, 609-20 (2008) [WB]
  4. Yoshino, M. et al., Immunol. Lett. 115, 131-137 (2008) [IHC]
  5. Jinushi, M., et al., J.Clin.Invest. 117, 1902-1913 (2007) [IHC]
  6. Hanayama, R., et al., PNAS 102, 16886-16891 (2005)
  7. Hanayama, R., et al., Science 304, 1147-1150 (2004)
  8. Miyasaka, K., et al., Eur. J. Immunol. 34, 1414-1422 (2004)
  9. Hanayama, R., et al., J. Immunol. 172, 3876-3882 (2004)
  10. Hanayama, R., et al., Nature 417, 182-187 (2002)
Code D199-3
Product Type Antibody
Size 100 μg
Application IHC, WB
Price
$284.06
Qty:

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