Anti-Granulysin (Human) mAb-Biotin

  • Applications
    • ELISA
  • Target Granulysin
  • Host Species Mouse
  • Species Reactivities Human
  • Code # D185-6
  • Size 100 µl
  • Price
    $311.90
Specifications

Background

Granulysin is an antimicrobial protein expressed on cytotoxic T cells, natural killer (NK) cells and NKT cells. It has been shown that Granulysin contributes to the defence mechanisms against variety of mycobacterial infection and tumors. Granulysin has two molecular forms, 15 kDa precursor and 9 kDa effector form. There serum levels were significantly elevated during the acute viral infections and correlated with the NK cell and CTL activities in patients with sever immunodeficiency, indicate that serum Granulysin could be useful novel marker to evaluate the overall status of host cell immunity.
  • Antibody Type:
    Monoclonal
  • Application:
    ELISA
  • Clone Number:
    RC8
  • Concentration:
    100 μg/ml
  • Conjugate:
    Biotin
  • Description:

    Monoclonal antibody conjugated to biotin of 100 µl targeting Granulysin for ELISA.

  • Formulation:
    10 μg IgG in 100 μl volume of PBS containing 1% BSA and 0.09% NaN3.*Azide may react with copper or lead in plumbing system to form explosive metal azides. Therefore, always flush plenty of water when disposing materials containing azide into drain.
  • Gene ID (Human):
  • Host Species:
    Mouse
  • Immunogen:
    Human full-length expression plasmid Guranyuraishin
  • Isotype:
    IgG1
  • Product Type:
    Antibody
  • Reactivity:
    This antibody is available for Granulysin ELISA.
  • Research Area:
    Apoptosis
  • Short Description:

    Granulysin Monoclonal Antibody.

  • Size:
    100 µl
  • Species Reactivity:
    Human
  • Storage Temperature:
    4°C
  • Target:
    Granulysin
Citations
  1. Pitabut N et al. Decreased plasma granulysin and increased interferon-gamma concentrations in patients with newly diagnosed and relapsed tuberculosis. Microbiol Immunol. 55, 565-73 (2011),
  2. Pitabut N et al. Potential function of granulysin, other related effector molecules and lymphocyte subsets in patients with TB and HIV/TB coinfection. Int J Med Sci. 10, 1003-14 (2013)
References
  1. Nakashima, A., et al., Am. J. Pathol. 173, 653-664 (2008)
  2. Ogawa, K., et al., Eur. J. Immunol. 33, 1925-1933 (2003)
  3. Gamen, S., et al., J. Immunol. 161, 1758-1764 (1998)