Anti-CD279 (PD-1) (Human) mAb-PE

Alternative Names

programmed death-1

Background

​Human PD-1 (programmed death-1) is a 55 kDa member of the immunoglobulin superfamily that is induced in cells undergoing apoptosis. The PD-1 protein contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) and is expressed predominantly on activated T and B lymphocytes. PD-1 plays a key role in autoimmune disease and is thought to be involved in the maintenance of peripheral self-tolerance by serving as a negative regulator of immune responses. Two novel members of the B7 family have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and up-regulation on activated antigen-presenting cells.

• Antibody Type:
  Monoclonal
• Application:
  FCM
• Clone Number:
  J105
• Conjugate:
  PE
• Description:

  Monoclonal antibody conjugated to PE of 50 tests targeting PD-1 for FCM.

• Formulation:
  50 tests in 1 mL volume of PBS containing 1% BSA and 0.09% NaN3.* Azide may react with copper or lead in plumbing systems to form explosive metal azides. Therefore, always flush drains thoroughly with plenty of water when disposing of materials containin
• Gene ID (Human):

  9825

• Gene ID (Mouse):

  263876

• Host Species:
  Mouse
• Immunogen:
  Extracellular domain of human PD-1
• Isotype:
  IgG1
• Product Type:
  Antibody
• Reactivity:
  This antibody reacts with human PD-1 on Flow cytometry.
• Research Area:
  Apoptosis
• Short Description:

  PD-1 Monoclonal Antibody.

• Size:
  50 Tests
• Species Reactivity:
  Human
• Storage Temperature:
  4°C
• Target:
  PD-1