Anti-Phosphorylated Vimentin (Ser50) mAb

  • Applications
    • ICC
    • WB
  • Target Vimentin
  • Host Species Rat
  • Species Reactivities Human, Mouse, Rat
  • Code # D122-3
  • Size 100 μg
  • Price
    $334.18
Specifications

Background

​Components of intermediate filaments provide information on the origin of vertebrate cells. Antibody to vimentin can be used as to identify the vimentin subclass of intermediate filaments. Vimentin is a ~58 kDa, widely expressed protein that thought to be involved mainly in structural processes, such as wound healing. Scientists have also recently determined that activated human macrophages secrete vimentin into the extracellular space, and overproduction of vimentin has been associated with cellular senescence.
  • Antibody Type:
    Monoclonal
  • Application:
    ICC, WB
  • Clone Number:
    TM50
  • Concentration:
    1 mg/mL
  • Conjugate:
    Unlabeled
  • Description:
    Monoclonal antibody of 100 μg targeting Vimentin for ICC, WB.
  • Formulation:
    100 μg IgG in 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative iscontained.
  • Gene ID (Human):
  • Gene ID (Mouse):
  • Host Species:
    Rat
  • Immunogen:
    KLH-PV50 peptide (CPSTSRpSLYSS)
  • Isotype:
    IgG2a
  • Product Type:
    Antibody
  • Reactivity:
    This antibody reacts with human, mouse and rat vimentin phosphorylated at Ser50.
  • Research Area:
    Cell Biology
  • Short Description:
    Vimentin Monoclonal Antibody.
  • Size:
    100 μg
  • Species Reactivity:
    Human, Mouse, Rat
  • Storage Temperature:
    -20°C
  • Target:
    Vimentin
References
  1. Oguri, T., et al., Genes Cells 11, 531-540 (2006)
  2. Yamaguchi, T., et al., J. Cell Biol. 171, 431-436 (2005)
  3. Stefanovic, S., et al., J. Virol. 79, 11766-11775 (2005)
  4. Goto, H., et al., Genes Cells 7, 91-97 (2002)
  5. Nakamura, Y., et al., Genes Cells 5, 823-837 (2000)
  6. Inagaki, N., et al., J. Biol. Chem. 275, 27165-27171 (2000)
  7. Goto, H., et al., J. Biol. Chem. 273, 11728-11736 (1998)
  8. Inagaki, N., et al., J. Biol. Chem. 272, 25195-25199 (1997)
  9. Takai, Y., et al., J. Cell Biol. 133, 141-149 (1996)