Anti-Mesothelin (Mouse) mAb-PE

  • Applications
    • FCM
  • Target Mesothelin/MPF
  • Host Species Rat
  • Species Reactivities Mouse
  • Code # D053-5
  • Size 50 Tests
  • Price
    $306.33
Specifications

Alternative Names

MSLN

Background

Mesothelin (MSLN) is a GPI-linked cell surface glycoprotein expressed in the mesothelial lining of the body cavities and in mullerian duct epithelium related cancer cells (ovarian, pancreatic cancer, mesothelioma). Both human and mouse mesothelin bind to ovarian cancer antigen CA125/MUC16 with high affinity, mediating cell attachment in vitro, suggesting that mesothelin may facilitate ovarian cancer metastasis.
  • Antibody Type:
    Monoclonal
  • Application:
    FCM
  • Clone Number:
    295D
  • Conjugate:
    PE
  • Description:
    Monoclonal antibody conjugated to PE of 50 tests targeting Mesothelin/MPF for FCM.
  • Formulation:
    50 tests in 1 mL volume of PBS containing 1% BSA and 0.09% NaN3.*Azide may react with copper orlead in plumbing system to form explosive metal azides. Therefore, always flush plenty ofwater when disposing materials containing azide into drain.
  • Gene ID (Human):
  • Gene ID (Mouse):
  • Host Species:
    Rat
  • Immunogen:
    Mouse cell-like cell line LO f Geo Blast Man
  • Isotype:
    IgG2a ĸ
  • Product Type:
    Antibody
  • Reactivity:
    This antibody reacts with mouse Mesothelin on Flow cytometry.
  • Research Area:
    Immunology
  • Short Description:
    Mesothelin/MPF Monoclonal Antibody.
  • Size:
    50 Tests
  • Species Reactivity:
    Mouse
  • Storage Temperature:
    4°C
  • Target:
    Mesothelin/MPF
References
  1. Gubbels, J. A., et al., Mol. Cancer 5, 50-64 (2006)
  2. Ho, M., et al., Clin. Cancer Res. 11, 3814-3820(2005)
  3. Rump, A., et al., J. Biol. Chem. 279, 9190-9198(2004)
  4. Nakayama, K., et al., J. Biol. Chem. 274, 24766-24772 (1999)
  5. Kojima, T., et al., J. Biol. Chem. 270, 21984-21990(1995)