Anti-IL-18 (Mouse) mAb-Biotin (Monoclonal Antibody)

IL-18 Monoclonal Antibody.

Specifications:

Description

Monoclonal antibody of 50 µl targeting IL-18 for ELISA.

Target: IL-18
Product Type: Antibody
Size: 50 μl
Application: ELISA
Research Area / Disease: Immunology
Conjugate: Biotin
Antibody Type: Monoclonal
Clone Number: 93-10C
Formulation: In 50 µl volume of PBS containing1% BSA, 10% glycerol and 0.09%sodiumazide, pH 7.2.*Azide may react with copper or lead in plumbing system to form explosive metalazides.Therefore, always flush plenty ofwater when disposing materials containing a
Isotype: IgG1
Immunogen: Recombinant mouse IL-18
Host Species: Rat
Species Reactivity: Mouse
Source: This antibody was purified fromhybridoma(clone93-10C) supernatantusing protein G agarose.Thishybridomawas establishedby fusion of mouse myelomacellSP2/0with SD rat splenocyte immunized withrecombinant mouse IL-18.
Reactivity: This antibody reacts with mouse IL-18on ELISA.
Gene ID Human:

3606

Gene ID Mouse:

16173

Storage Temperature: 4°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Citations

  1. Abu Elhija M et al. Over-expression of IL-18, ICE and IL-18 R in testicular tissue from sexually immature as compared to mature mice. Eur Cytokine Netw. 19, 15-24 (2008)(PMID:18299270)
  2. Abu Elhija M et al. LPS increases the expression levels of IL-18, ICE and IL-18 R in mouse testes. Am J Reprod Immunol. 2008 60, 361-71 (2008)(PMID:19046143)
  3. Wang X et al. The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation. Infect Immun. 84, 1796-1805 (2016)(PMID:27045038)
  4. Wang X et al. The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation. PLoS Pathog. 12, e1005803 (2016)(PMID:27482714)
  5. Lasseaux C et al. Type I interferons drive inflammasome-independent emergency monocytopoiesis during endotoxemia. Sci Rep. 7, 16935 (2017)(PMID:29209091)
  6. Nichols RD et al. NAIP/NLRC4 inflammasome activation in MRP8+ cells is sufficient to cause systemic inflammatory disease. Nat Commun. 8, 2209 (2017)(PMID:29263322)
  7. Flood B et al. Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis. Oncogene. 38, 2658-2674 (2019)(PMID:30538296)

References

  1. Dao, T., et al., Cell Immunol. 173, 230-235 (1996)
  2. Micallef, M., et al., Eur. J. Immunol. 26, 1647-1651 (1996)
  3. Ushio, S., et al., J. Immunol. 156, 4274-4279 (1996)
  4. Okamura, H., et al., Nature 378, 88-91 (1995)
Code D048-6
Product Type Antibody
Size 50 μl
Application ELISA
Price
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