Anti-IL-18 (Human) mAb-Biotin (Monoclonal Antibody)
IL-18 Monoclonal Antibody.
Specifications:
Description
Monoclonal antibody of 50 µl targeting IL-18 for ELISA.
| Target: | IL-18 |
|---|---|
| Product Type: | Antibody |
| Size: | 50 μl |
| Application: | ELISA |
| Research Area / Disease: | Immunology |
| Conjugate: | Biotin |
| Antibody Type: | Monoclonal |
| Clone Number: | 159-12B |
| Concentration: | 500 μg/ml |
| Formulation: | 25µg IgG in 50 µl volume of PBS containing 1% BSA and 0.09% NaN3 |
| Isotype: | IgG2a |
| Immunogen: | Recombinant human IL-18 |
| Host Species: | Rat |
| Species Reactivity: | Human |
| Source: | This antibody was purified from mouse ascites fluid using protein A agarose. This hybridoma was established by fusion of mouse myeloma cell SP2/0 with Balb/c mouse splenocyte immunized with recombinant human IL-18. |
| Reactivity: | This antibody reacts with human IL-18on ELISA. |
| Gene ID Human: | |
| Gene ID Mouse: | |
| Storage Temperature: | 4°C |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
Citations
- Giavedoni LD. Simultaneous detection of multiple cytokines and chemokines from nonhuman primates using luminex technology. J Immunol Methods. 301, 89-101 (2005)(PMID:15896800)
- Leach ST et al. Local and systemic interleukin-18 and interleukin-18-binding protein in children with inflammatory bowel disease. Inflamm Bowel Dis.
14, 68-74 (2008)(PMID:17879274) - Bontkes HJ et al. Tumor associated antigen and interleukin-12 mRNA transfected dendritic cells enhance effector function of natural killer cells and antigen specific T-cells. Clin Immunol. 127, 375-94 (2008)(PMID:18358784)
- Okano M et al. Characterization of IL-18 expression and release in the pathogenesis of chronic rhinosinusitis. Int Arch Allergy Immunol. 160, 275-86 (2013)(PMID:23075512)
- Thinwa J et al. Integrin-media,ted first signal for inflammasome activation in intestinal epithelial cells. J Immunol. 193, 1373-82 (2014)(PMID:24965773)
- Furman D et al. Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states. Nat Med. 23, 174-184 (2017)(PMID:28092664)
- Lagrange B et al. Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11. Nat Commun. 9, 242 (2018)(PMID:29339744)
- Pal A et al. Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides. Sci Rep. 9, 4913 (2019)(PMID:30894604)
References
- McCurnin, D., et al., Pediatrics 121, 945-956 (2008)
- Haveman, L. M., et al., Int. Immunol. 18, 1521-1529 (2006)
- Shigehara, K., et al., J. Immunol. 166, 642-649 (2001)
- Dao, T., et al. Cell Immunol. 173, 230-235 (1996)
- Micallef, M., et al. Eur. J. Immunol. 26, 1647-1651 (1996)
- Ushio, S., et al. J. Immunol. 156, 4274-4279 (1996)
- Okamura, H., et al. Nature 378, 88-91 (1995)
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