Anti-IL-18 (Human) mAb-Biotin (Monoclonal Antibody)

IL-18 Monoclonal Antibody.

Specifications:

Description

Monoclonal antibody of 50 µl targeting IL-18 for ELISA.

Target: IL-18
Product Type: Antibody
Size: 50 μl
Application: ELISA
Research Area / Disease: Immunology
Conjugate: Biotin
Antibody Type: Monoclonal
Clone Number: 159-12B
Concentration: 500 μg/ml
Formulation: 25µg IgG in 50 µl volume of PBS containing 1% BSA and 0.09% NaN3
Isotype: IgG2a
Immunogen: Recombinant human IL-18
Host Species: Rat
Species Reactivity: Human
Source: This antibody was purified from mouse ascitesfluid using proteinA agarose. This hybridoma wasestablished by fusion of mouse myeloma cell SP2/0 withBalb/c mouse splenocyte immunized with recombinanthuman IL-18.
Reactivity: This antibody reacts with human IL-18on ELISA.
Gene ID Human:

3606

Gene ID Mouse:

16173

Storage Temperature: 4°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

Citations

  1. Giavedoni LD. Simultaneous detection of multiple cytokines and chemokines from nonhuman primates using luminex technology. J Immunol Methods. 301, 89-101 (2005)(PMID:15896800)
  2. Leach ST et al. Local and systemic interleukin-18 and interleukin-18-binding protein in children with inflammatory bowel disease. Inflamm Bowel Dis.
    14, 68-74 (2008)(PMID:17879274)
  3. Bontkes HJ et al. Tumor associated antigen and interleukin-12 mRNA transfected dendritic cells enhance effector function of natural killer cells and antigen specific T-cells. Clin Immunol. 127, 375-94 (2008)(PMID:18358784)
  4. Okano M et al. Characterization of IL-18 expression and release in the pathogenesis of chronic rhinosinusitis.  Int Arch Allergy Immunol. 160, 275-86 (2013)(PMID:23075512)
  5. Thinwa J et al. Integrin-media,ted first signal for inflammasome activation in intestinal epithelial cells. J Immunol. 193, 1373-82 (2014)(PMID:24965773)
  6. Furman D et al. Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states. Nat Med. 23, 174-184 (2017)(PMID:28092664)
  7. Lagrange B et al. Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11. Nat Commun. 9, 242 (2018)(PMID:29339744)
  8. Pal A et al. Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides. Sci Rep. 9, 4913 (2019)(PMID:30894604)

References

  1. McCurnin, D., et al., Pediatrics 121, 945-956 (2008)
  2. Haveman, L. M., et al., Int. Immunol. 18, 1521-1529 (2006)
  3. Shigehara, K., et al., J. Immunol. 166, 642-649 (2001)
  4. Dao, T., et al. Cell Immunol. 173, 230-235 (1996)
  5. Micallef, M., et al. Eur. J. Immunol. 26, 1647-1651 (1996)
  6. Ushio, S., et al. J. Immunol. 156, 4274-4279 (1996)
  7. Okamura, H., et al. Nature 378, 88-91 (1995)
Code D045-6
Product Type Antibody
Size 50 μl
Application ELISA
Price
$311.90
Qty: