14-3-3 γ (Human)

  • Code # CY-R2143
  • Size 100 µg
  • Price
    $306.33
Specifications

Alternative Names

Tyrosine 3-Monooxygenase, Tryptophan 5-Monooxygenase Activation Protein γ Isoform, YWHAG, 14-3-3γ

Background

14-3-3 protein family is highly conserved from plants to mammals and ubiquitously expressed cellular proteins. In mammals, there are seven isoforms encoded by a distinct gene (Beta, Epsilon, Gamma, Sigma, Eta, Tau and Zeta). More than 200 target proteins of the 14-3-3 protein family have been identified. Interactions of 14-3-3 proteins and the target proteins are dependent on phosphorylation of serine/threonine residue on the target proteins with some exceptions. 14-3-3 is deeply and widely involved in mitogenic signaling, cell cycle regulation and cell death/survival, suggesting the family plays important role in human neoplastic and neurological diseases.
  • Description:

    14-3-3 γ (Human) of 100 µg and Recombinant human 14-3-3 Gamma demonstrates approximately 54 kDa band by SDS-PAGE analysis.

  • Formulation:
    Recombinant human 14-3-3 γ is supplied frozen in phosphate buffered saline (PBS) containing 50 % glycerol.
  • Gene ID (Human):
  • Gene ID (Mouse):
  • Product Type:
    Recombinant Protein
  • Research Area:
    Autophagy
  • Short Description:

    14-3-3 γ (Human).

  • Size:
    100 µg
  • Storage Temperature:
    -70°C
References
  1. Mackintosh C. Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes. Biochem J. 2004 Jul 15;381(Pt 2):329-42.
  2. Dougherty MK, Morrison DK. Unlocking the code of 14-3-3. J Cell Sci. 2004 Apr 15;117(Pt 10):1875-84.
  3. Hermeking H. The 14-3-3 cancer connection. Nat Rev Cancer. 2003 Dec;3(12):931-43.
  4. Berg D, Holzmann C, Riess O. 14-3-3 proteins in the nervous system. Nat Rev Neurosci. 2003 Sep;4(9):752-62.