Anti-S100A6 pAb (Polyclonal Antibody)

Anti-S100A6 Polyclonal Antibody.

Specifications:

Description

Polyclonal Antibody of 50 µg targeting S100A6 for WB.

Target: S100A6
Product Type: Antibody
Size: 50 µg
Application: WB
Research Area / Disease: Immunology, Neuroscience
Conjugate: Unlabeled
Antibody Type: Polyclonal
Concentration: 1.0 μg/μL
Formulation: 20 mM phosphate buffer (pH 7.5), 300 mM NaCl, 50 % glycerol.
Isotype: IgG
Immunogen: recombinant human S100A6, corresponding full length of human S100A6, expressed in E. coli
Host Species: Rabbit
Species Reactivity: Human
Source: The antibody is produced by immunizing rabbit with a recombinant human S100A6, corresponding full length of human S100A6, expressed in E. coli. IgG is purified by immunoaffinity chromatography.
Storage Temperature: -20°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

References

  1. Heizmann, C.W., and Cox, J.A.; New perspectives on S100 proteins: a multi-functional Ca2+-, Zn2+- and Cu2+- binding protein family. BioMetals 11, 383-397, 1998
  2. Donato, R.; Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type. Biochim. Biophys. Acta 1450, 191-231, 1999
  3. Donato, R.; S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. Int. J. Biochem. Cell Biol. 33:637-668, 2001
  4. Stulík J, Österreicher J, Koupilová K, Knížek J, Bureš J, Jandík P, Langr F, Dědič K, Schäfer BW, Heizmann CW.; Differential expression of the Ca2+ binding S100A6 protein in normal, preneoplastic and neoplastic colon mucosa. Eur. J. Cancer 36, 1050-1059, 2000
  5. Seth A, Lee BK, Qi S, Vary CP.; Coordinate expression of novel genes during osteoblast differentiation. J. Bone Miner. Res. 15, 1683-1696, 2000
  6. Weterman MA, Stoopen GM, van Muijen GN, Kuznicki J, Ruiter DJ, Bloemers HP.; Expression of calcyclin in human melanoma cell lines correlates with metastatic behavior in nude mice. Cancer Res. 52, 1291-1296, 1992
  7. Calabretta B, Battini R, Kaczmarek L, de Riel JK, Baserga R. Molecular cloning of the cDNA for a growth factor-inducible gene with strong homology to S-100, a calcium-binding protein. J. Biol. Chem. 261, 12628-12632, 1986
  8. Calabretta B, Venturelli D, Kaczmarek L, Narni F, Talpaz M, Anderson B, Beran M, Baserga R.; Altered expression of G1-specific genes in human malignant myeloid cells. Proc Natl Acad Sci U S A. 83, 1495-1498, 1986
  9. Okazaki K, Niki I, Iino S, Kobayashi S, Hidaka H; A role of calcyclin, a Ca2+-binding protein, on Ca2+-dependent insulin release in the pancreatic β cell. J. Biol. Chem. 269, 6149-6152, 1994
  10. Thordarson, G., Southard, J.N., Talamantes, F.; Purification and characterization of mouse decidual calcyclin: A novel stimulator of mouse placental lactogen-II secretion Endocrinology 129, 1257-1265, 1991
  11. Boom A, Pochet R, Authelet M, Pradier L, Borghgraef P, Van Leuven F, Heizmann CW, Brion J-P. ; Astrocytic calcium/zinc binding protein S100A6 over expression in alzheimer’s disease and in PS1/APP transgenic mice models. Biochim. Biophys. Acta 1742, 161-168, 2004
  12. Hoyaux D., Boom A., Van den Bosch L., Belot N., Martin J.J., Heizmann C.W., Kiss R., Pochet R.; S100A6 overexpression within astrocytes associated with impaired axons from both ALS mouse model and human patients. J. Neuropathol. Exp. Neurol. 61, 736-744, 2002
Code CY-P1042
Product Type Antibody
Size 50 µg
Application WB
Price
$328.61
Qty: