Anti-PCSK9 (Human) mAb (Monoclonal Antibody)

Anti-PCSK9 (Human) Monoclonal Antibody.

Specifications:

Description

Monoclonal Antibody of 100 μg targeting PCSK9 for IP, WB.

Target: PCSK9
Product Type: Antibody
Size: 100 μg
Application: IP, WB
Research Area / Disease: Metabolism
Conjugate: Unlabeled
Antibody Type: Monoclonal
Clone Number: KS-4H12
Concentration: 1.0 mg/mL
Formulation: Supplied in 20mM phosphatase buffer (pH 7.5), 300mM NaCl, 50% glycerol.
Isotype: IgG1
Immunogen: Cells were expressed in 293 His-tagged Human PCSK9 (full length)
Host Species: Mouse
Species Reactivity: Human
Source: Monoclonal antibody is produced by immunizing mice with a His-tagged- PCSK9, corresponding full length of human PCSK9, expressed in 293 cells. IgG is purified by protein A-Sepharose chromatography.
Storage Temperature: -20°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.

References

  1. Seidah NG, Benjannet S, Wickham L, Marcinkiewicz J, Jasmin SB, Stifani S, Basak A, Prat A, Chretien M (2003) Proc Natl Acad Sci USA 100: 928-933.
  2. Abifadel M, Varret M, Rabes JP, Allard D, Ouguerram K, Devillers M, Cruaud C, Benjannet S, Wickham L, Erlich D, et al. (2003) Nat Genet 34: 154-156.
  3. Leren TP (2004) Clin Genet 65: 419-422.
  4. Allard D, Amsellem S, Abifadel M, Trillard M, Devillers M, Luc G, Krempf M, Reznik Y, Girardet JP, Fredenrich A, et al. (2005) Hum Mutat 26: 497.
  5. Cohen JC, Boerwinkle E, Mosley TH, Jr, Hobbs HH (2006) N Engl J Med 354: 1264-1272.
  6. Berge KE, Ose L, Leren TP (2006) Arterioscler Thromb Vasc Biol 26: 1094-1100.
  7. Maxwell KN, Breslow JL (2004) Proc Natl Acad Sci USA 101: 7100-7105.
  8. Rashid S, Curtis DE, Garuti R, Anderson NN, Bashmakov Y, Ho YK, Hammer RE, Moon YA, Horton JD (2005) Proc Natl Acad Sci USA 102: 5374-5379.
  9. Lagace, T. A., Curtis, D. E., Garuti, R., McNutt, M. C., Park, S. W., Prather, H. B., Anderson, N. N., Ho, Y. K., Hammer, R. E., and Horton, J. D. (2006) J. Clin. Investig. 116: 2995-3005
  10. Cameron, J., Holla, O. L., Ranheim, T., Kulseth, M. A., Berge, K. E., and Leren, T. P. (2006) Hum. Mol. Genet. 15: 1551-1558
  11. Zhang, D. W., Lagace, T. A., Garuti, R., Zhao, Z., McDonald, M., Horton, J. D., Cohen, J. C., and Hobbs, H. H. (2007) J. Biol. Chem. 282: 18602-18612
Code CY-M1033
Product Type Antibody
Size 100 μg
Application IP, WB
Price
$401.02
Qty:

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