Anti-Acetylated Histone/p53 (Lys382) mAb (Monoclonal Antibody) (Discontinued)
Anti-Acetylated Histone/p53 (Lys382) Monoclonal Antibody.
Specifications:
Description
We are sorry for the inconvenience; this product code has been discontinued.
Monoclonal Antibody of 100 μg targeting p53 for ELISA, IF, WB.
| Target: | p53 |
|---|---|
| Product Type: | Antibody |
| Size: | 100 μg |
| Application: | ELISA, IF, WB |
| Research Area / Disease: | Cancer |
| Conjugate: | Unlabeled |
| Antibody Type: | Monoclonal |
| Clone Number: | TM-5C5 |
| Concentration: | 1.0 mg/mL |
| Formulation: | Supplied in 20mM phosphatase buffer (pH 7.5), 300mM NaCl, 50% glycerol. |
| Isotype: | IgG1 |
| Immunogen: | Acetylated peptide synthesis near Lys382 of human p53 (binding KLH) |
| Host Species: | Mouse |
| Species Reactivity: | Human |
| Source: | This monoclonal antibody was produced by immunizing mouse with a synthetic acetylated (KLH coupled) corresponding to residues surrounding Lys382 of human p53. The IgG fraction was purified by protein A-Sepharose chromatography. |
| Reactivity: | The Acetylated Histone/p53 (Lys382) Monoclonal Antibody (TM-5C5) detects endogenousacetylated Histones (14.4-21.5 kDa) and severalacetylated protein including acetylated p53 (acetylatedlysine 382) . The antibody does not recognizenon-acetylated Histo |
| Storage Temperature: | -20°C |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
Citations
- Li Y, Matsumori H, Nakayama Y, Osaki M, Kojima H, Kurimasa A, Ito H, Mori S, Katoh M, Oshimura M, Inoue T.; SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis. Genes Cells. 16:34-45. 2011
References
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