Anti-Acetylated Histone/p53 (Lys382) mAb (Monoclonal Antibody) (Discontinued)

Anti-Acetylated Histone/p53 (Lys382) Monoclonal Antibody.



We are sorry for the inconvenience; this product code has been discontinued.

Monoclonal Antibody of 100 μg targeting p53 for ELISA, IF, WB.

Target: p53
Product Type: Antibody
Size: 100 μg
Application: ELISA, IF, WB
Research Area / Disease: Cancer
Conjugate: Unlabeled
Antibody Type: Monoclonal
Clone Number: TM-5C5
Concentration: 1.0 mg/mL
Formulation: Supplied in 20mM phosphatase buffer (pH 7.5), 300mM NaCl, 50% glycerol.
Isotype: IgG1
Immunogen: Acetylated peptide synthesis near Lys382 of human p53 (binding KLH)
Host Species: Mouse
Species Reactivity: Human
Source: This monoclonal antibody was produced by immunizing mouse with a synthetic acetylated (KLH coupled) corresponding to residues surrounding Lys382 of human p53. The IgG fraction was purified by protein A-Sepharose chromatography.
Reactivity: The Acetylated Histone/p53 (Lys382) Monoclonal Antibody (TM-5C5) detects endogenousacetylated Histones (14.4-21.5 kDa) and severalacetylated protein including acetylated p53 (acetylatedlysine 382) . The antibody does not recognizenon-acetylated Histo
Storage Temperature: -20°C
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.


  1. Li Y, Matsumori H, Nakayama Y, Osaki M, Kojima H, Kurimasa A, Ito H, Mori S, Katoh M, Oshimura M, Inoue T.; SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis. Genes Cells. 16:34-45. 2011


  1. Davie, J. R & Chadee, D. N. J. Cell Biochem. (Suppl.) 30-31, 203-213, 1998
  2. Kouzarides, T. Curr. Opin. Genet. Dev. 9, 40-84, 1999
  3. Fenrick, R. & Hiebert, S.W. J. Cell Biochem. (Suppl.) 30-31, 194-202, 1998
  4. Yoshida, M., Horinouchi, S. & Beppu, T. Bioassays 17, 423-430, 1995
  5. Richon, V. M. et al. Proc. Natl. Acad. Sci. USA 93, 5705-5708, 1996
  6. Richon, V. M. et al. Proc. Natl. Acad. Sci. USA 95, 3003-3007, 1998
  7. Cohen, L. et al. Proc. AACR 39, 108, abstr. 736, 1998
  8. Desai, D., El-Bayoumy, K. & Amin, S. Proc. AACR 40, 2396, abstr. 362, 1999
  9. Laherty, C. D., Yang, W-M. et al Cell 89, 349-356, 1997
  10. Hassig, C., Fleischer, T. C. et al Cell 89, 341-347, 1997
  11. Hoffmann, K., Grosch, G. & Jung, M. Nucleic Acids Res. 27, 2057-2058, 1999
Code CY-M1029
Product Type Antibody
Size 100 μg
Application ELISA, IF, WB
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