CircuLex Human PCSK9 Functional Assay Kit
This kit is primarily designed for the semi-quantitative in vitro measurement of functionally active of PCSK9 in serum and plasma, which is capable of binding to LDL receptor (LDLR). This kit allows to measure active PCSK9 in a solid-phase assay system based on a conventional ELISA in a semi-quantitative manner.
|Research Area / Disease:||Metabolism|
|Sensitivity:||0.042 mAU/mL -|
|Measurement Range:||0.125 - 8 mAU/mL|
|Regulatory Statement:||For Research Use Only. Not for use in diagnostic procedures.|
- Ben Djoudi Ouadda A et al. Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor).Arterioscler Thromb Vasc Biol. 39, 1996-2013 (2019)rn